Bibliographic Details
| Title: |
Chronic Active Epstein-Barr Virus (EBV) Infection Controlled by Allogeneic Stem Cell Transplantation and EBV-Specific T Cells. |
| Authors: |
Meedt, Elisabeth, Weber, Daniela, Bonifacius, Agnes, Eiz-Vesper, Britta, Maecker-Kolhoff, Britta, Delecluse, Susanne, Delecluse, Henri-Jacques, Lorenz, Myriam, Schwarz, Klaus, Meedt, Stefan T, Braess, Jan, Herr, Wolfgang, Holler, Ernst, Edinger, Matthias, Wolff, Daniel |
| Source: |
Clinical Infectious Diseases; 6/15/2023, Vol. 76 Issue 12, p2200-2202, 3p |
| Subject Terms: |
TREATMENT of Epstein-Barr virus diseases, HOMOGRAFTS, GRAFT versus host disease, CHRONIC diseases, CELLS, VIREMIA, HEMATOPOIETIC stem cell transplantation, T cells, IMMUNOSUPPRESSIVE agents, DISEASE remission |
| Abstract: |
We report sustained remission of chronic active Epstein-Barr virus (EBV) infection in a 27-year-old female patient treated with third-party EBV-specific T cells followed by allogeneic hematopoietic stem cell transplantation (HSCT). The viremia cleared after administration of anti-T-lymphocyte globulin for graft-versus-host disease (GvHD) prophylaxis. Subsequent expansion of EBV-infected host T cells was controlled by transfusion of donor-derived EBV-specific T cells. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
