Bibliographic Details
| Title: |
Clinical Correlation of Adenoviral Load in the Respiratory Tract Measured by Digital PCR in Immunocompromised Children. |
| Authors: |
Hijano, Diego R, Ferrolino, Jose A, Hidinger, Jennifer, Brazelton, Jessica N, Gu, Zhengming, Suganda, Sri, Glasgow, Heather L, Allison, Kim J, Peterson, Megan, Dallas, Ronald H, Maron, Gabriela, Hayden, Randall T |
| Source: |
Open Forum Infectious Diseases; Feb2023, Vol. 10 Issue 2, p1-6, 6p |
| Abstract: |
Immunocompromised patients can have life-threatening adenoviral infection. Viral load in blood and stool is commonly used to guide antiviral therapy. We developed and evaluated a digital polymerase chain reaction assay to quantify human adenovirus in the respiratory tract and showed that higher peak load correlates with disseminated infection, mechanical ventilation, and death. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
