Bibliographic Details
| Title: |
Baseline health-related quality of life predicts falls: a secondary analysis of a randomized controlled trial. |
| Authors: |
Davis, Jennifer C., Hsu, Chun Liang, Ghag, Cheyenne, Starkey, Samantha Y., Jacova, Patrizio, Dian, Larry, Parmar, Naaz, Madden, Kenneth, Liu-Ambrose, Teresa |
| Source: |
Quality of Life Research; Nov2022, Vol. 31 Issue 11, p3211-3220, 10p, 3 Charts |
| Subject Terms: |
OLDER people, QUALITY of life, CLINICAL trials, ACCIDENTAL falls, EXERCISE |
| Abstract: |
Purpose: Among older adults, health-related quality of life (HRQoL) and falls are associated. Generic patient-reported outcomes measures (PROMs) assess individual's HRQoL. The role for PROMs, a potential tool for predicting subsequent falls, remains under-explored. Our primary aim was to determine whether a baseline PROMs assessment of HRQoL may be a useful tool for predicting future falls.Methods: A secondary analysis of a 12-month randomized clinical trial (RCT) of a home-based exercise program among 344 adults (67% female), aged ≥ 70 years, with ≥ 1 falls in the prior year who were randomized (1:1) to either a home-based exercise program (n = 172) or usual care (n = 172). A negative binomial regression model with total falls count as the dependent variable evaluated the main effect of the independent variable-baseline HRQoL (measured by the Short-Form-6D)-controlling for total exposure time and experiment group (i.e., exercise or usual care) for the total sample. For the usual care group alone, the model controlled for total exposure time.Results: For the total sample, the rate of subsequent total falls was significantly predicted by baseline HRQoL (IRR = 0.044; 95% CI [0.005-0.037]; p = .004). For the usual care group, findings were confirmed with wider confidence intervals and the rate of prospective total falls was significantly predicted by baseline HRQoL (IRR = 0.025; 95% CI [0.001-0.909]; p = .044).Conclusion: These findings suggest the ShortForm-6D should be considered as part of falls prevention screening strategies within a Falls Prevention Clinic setting. Trial Registrations ClinicalTrials.gov Protocol Registration System. Identifier: NCT01029171; URL: https://clinicaltrials.gov/ct2/show/NCT01029171 . Identifier: NCT00323596; URL: https://clinicaltrials.gov/ct2/show/NCT00323596 . [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
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