Bibliographic Details
| Title: |
Building a neurocognitive profile of suicidal risk in severe mental disorders. |
| Authors: |
Comparelli, Anna, Corigliano, Valentina, Montalbani, Benedetta, Nardella, Adele, De Carolis, Antonella, Stampatore, Lorenzo, Bargagna, Paride, Forcina, Francesca, Lamis, Dorian, Pompili, Maurizio |
| Source: |
BMC Psychiatry; 9/26/2022, Vol. 22 Issue 1, p1-8, 8p, 2 Charts, 1 Graph |
| Subject Terms: |
MENTAL illness, MULTIVARIATE analysis, ATTEMPTED suicide, SUICIDAL ideation, SUICIDE risk factors, SOCIAL perception |
| Abstract: |
Background: Research on the influence of neurocognitive factors on suicide risk, regardless of the diagnosis, is inconsistent. Recently, suicide risk studies propose applying a trans-diagnostic framework in line with the launch of the Research Domain Criteria Cognitive Systems model. In the present study, we highlight the extent of cognitive impairment using a standardized battery in a psychiatric sample stratified for different degrees of suicidal risk. We also differentiate in our sample various neurocognitive profiles associated with different levels of risk. Materials and methods: We divided a sample of 106 subjects into three groups stratified by suicide risk level: Suicide Attempt (SA), Suicidal Ideation (SI), Patient Controls (PC) and Healthy Controls (HC). We conducted a multivariate Analysis of Variance (MANOVA) for each cognitive domain measured through the standardized battery MATRICS Consensus Cognitive Battery (MCCB). Results: We found that the group of patients performed worse than the group of healthy controls on most domains; social cognition was impaired in the suicide risk groups compared both to HC and PC. Patients in the SA group performed worse than those in the SI group. Conclusion: Social cognition impairment may play a crucial role in suicidality among individuals diagnosed with serious mental illness as it is involved in both SI and SA; noteworthy, it is more compromised in the SA group fitting as a marker of risk severity. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
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