Bibliographic Details
| Title: |
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placental Infection Is Associated With Massive Perivillous Fibrin Deposition at the Maternal-Fetal Interface: A Preliminary Study. |
| Authors: |
Kotiloglu-Karaa, Esin, Kele, Beatrix, Kulasegaran-Shylini, Raghavendran, Broad, Claire E, Owoyemi, Dola, Martin, Joanne, MacPhail, Graham, Iliodromiti, Stamatina, Riddell, Anna, Alexander, Eliza, Cutino-Moguel, Teresa |
| Source: |
Clinical Infectious Diseases; Jul2022, Vol. 75 Issue 1, pe1176-e1179, 4p |
| Subject Terms: |
REVERSE transcriptase polymerase chain reaction, COVID-19, PLACENTA diseases, IMMUNOHISTOCHEMISTRY, SEVERITY of illness index, FIBRIN, DISEASE risk factors, PREGNANCY |
| Abstract: |
We observed an increased frequency of massive perivillous fibrin deposition (MPFD) during the second coronavirus disease 2019 (COVID-19) pandemic wave dominated by the Alpha variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MPFD associated with 100% reverse transcription polymerase chain reaction (RT-PCR) positivity for SARS-CoV-2 and detection by immunohistochemistry. The Alpha variant was identified in all placentas with MPFD that could be sequenced. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
