Bibliographic Details
| Title: |
Proper assignation of reactivation in a COVID-19 recurrence initially interpreted as a reinfection. |
| Authors: |
Pérez-Lago, Laura, Martínez-Lozano, Helena, Díaz, Jose Antonio Pajares, Gómez, Arantxa Díaz, Machado, Marina, Sola-Campoy, Pedro J, Herranz, Marta, Buenestado-Serrano, Sergio, Valerio, Maricela, Olmedo, María, Zayas, Cristina Andrés, Comas, Iñaki, Candelas, Fernando González, Bañares, Rafael, Catalán, Pilar, Muñoz, Patricia, Viedma, Darío García de, Pajares Díaz, Jose Antonio, Díaz Gómez, Arantxa, Andrés Zayas, Cristina |
| Source: |
Journal of Infectious Diseases; Sep2021, Vol. 224 Issue 5, p788-792, 5p |
| Subject Terms: |
COVID-19, REINFECTION, COVID-19 pandemic, SARS-CoV-2, COVID-19 testing |
| Abstract: |
A 77-year-old-male (Case R) who had had a previous diagnosis of mild COVID-19 episode, was hospitalized 35 days later. On Day 23 post-admission, he developed a second COVID-19 episode, now severe, and finally died. Initially, Case R COVID-19 recurrence was interpreted as a reinfection due to the exposure to a SARS-CoV-2 RT-PCR-positive room-mate. However, whole-genome-sequencing indicated that case R recurrence corresponded to a reactivation of the strain involved in his first episode. Case R reactivation had major consequences, leading to a more severe episode, and causing a subsequent transmission to another two hospitalized patients, one of them with fatal outcome. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
