Editorial: Fetal-Maternal Immune Interactions in Pregnancy.

Bibliographic Details
Title: Editorial: Fetal-Maternal Immune Interactions in Pregnancy.
Authors: Than, Nandor Gabor, Hahn, Sinuhe, Rossi, Simona W., Szekeres-Bartho, Julia
Source: Frontiers in Immunology; 11/27/2019, Vol. 10, p1-4, 4p
Subject Terms: PREGNANCY, PREGNANCY complications, AMNIOTIC liquid, SUPPRESSOR cells, BIOLOGICAL transport, PREECLAMPSIA
Abstract: While self-reactive Treg cells contribute to the maintenance of self-tolerance, paternal antigen-specific T cells control the immune response to paternal antigen expressing cells. Paternal antigen-specific Treg cells accumulate in the murine placenta, and recent studies have identified these cells at the feto-maternal interface of humans. Because inflammation is implicated as a causal factor in preeclampsia and because Treg cells are able to control inflammation, the paper of Robertson et al. discusses the potential therapeutic use of Treg cells. The altered expression of galectins is associated with infertility and pregnancy complications, and their potential therapeutic role in pregnancy complications is also suggested. [Extracted from the article]
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Database: Complementary Index
More Details
ISSN:16643224
DOI:10.3389/fimmu.2019.02729
Published in:Frontiers in Immunology
Language:English