Bibliographic Details
| Title: |
Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial. |
| Authors: |
Liu, Shi-wei, Guo, Jie, Wu, Wei-kang, Chen, Ze-liang, Zhang, Ning |
| Source: |
Chinese Journal of Integrative Medicine; Jan2019, Vol. 25 Issue 1, p16-22, 7p |
| Subject Terms: |
DISEASE relapse prevention, COMMUNITY health services, HERBAL medicine, HOSPITALS, CHINESE medicine, STATISTICAL sampling, URINARY tract infections, DISEASE relapse, RANDOMIZED controlled trials, TREATMENT effectiveness, BLIND experiment, DESCRIPTIVE statistics |
| Abstract: |
Objective: To evaluate Chinese medicine (CM) formula Bazheng Powder (八正散) as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI).Methods: A randomized double-blinded trial was performed. Eligible female patients with RUTI were recruited from one hospital and two community health centers. By using a blocked randomization scheme, participants were randomized to receive a CM formula (10 herbs) for 4 weeks or antibiotics for 1 week, followed by 3 weeks of placebo. Clinical cure rate and microbiological cure and recurrence after treatment were evaluated.Results: A total 122 eligible patients were enrolled, with 61 cases in each group. The clinical cure rate by the intentto- treatment approach was 90.2% for the CM group and 82.0% for the antibiotics group (P>0.05). Bacteria were cleared from 88.5% (54/61) of patients in the CM group and 82.0% (50/61) in the antibiotics group. The recurrence rate in recovered patients at the 6-month follow-up was 9.1% (5/61) and 14.0 (7/61) in the CM and antibiotics groups, respectively (P>0.05).Conclusion: CM formula Bazheng Powder is a good alternative option for RUTI treatment. (Registration No. NCT01745328) [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
