Occupational exposure to flour dust and the risk of head and neck cancer.
| Title: | Occupational exposure to flour dust and the risk of head and neck cancer. |
|---|---|
| Authors: | Carton, Matthieu, Menvielle, Gwenn, Cyr, Diane, Sanchez, Marie, Pilorget, Corinne, Guizard, Anne‐Valérie, Stücker, Isabelle, Luce, Danièle, for the Icare Study Group |
| Source: | American Journal of Industrial Medicine; Oct2018, Vol. 61 Issue 10, p869-873, 5p |
| Subject Terms: | HEAD & neck cancer, SQUAMOUS cell carcinoma, OCCUPATIONAL hazards, ALCOHOL drinking, LOGISTIC regression analysis |
| Abstract: | Background: To investigate the association between head and neck squamous cell cancer (HNSCC) risk and occupational exposure to flour dust in women and men, using data from ICARE, a French population‐based case‐control study. Methods: The analysis included 2053 cases of HNSCC and 3507 controls. Lifelong occupational history was collected. A job‐exposure matrix was used to assess exposure to flour dust. Odds‐ratios (ORs) and 95% confidence intervals (CI), adjusted for smoking, alcohol drinking, and asbestos exposure, were estimated with logistic regression models. Results: Ever exposure to flour dust was associated with elevated ORs in women (OR = 2.15, 95%CI: 1.01 4.55) and in men (OR = 1.55, 95%CI: 1.11 2.17). In women, the risk increased with the probability, the duration, and the cumulative level of exposure. No dose‐response relationships were observed in men. Conclusions: Although the results were less conclusive in men than in women, overall, these findings provide some support to the hypothesis of a role of flour dust in the occurrence of HNSCC. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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| Items | – Name: Title Label: Title Group: Ti Data: Occupational exposure to flour dust and the risk of head and neck cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Carton%2C+Matthieu%22">Carton, Matthieu</searchLink><br /><searchLink fieldCode="AR" term="%22Menvielle%2C+Gwenn%22">Menvielle, Gwenn</searchLink><br /><searchLink fieldCode="AR" term="%22Cyr%2C+Diane%22">Cyr, Diane</searchLink><br /><searchLink fieldCode="AR" term="%22Sanchez%2C+Marie%22">Sanchez, Marie</searchLink><br /><searchLink fieldCode="AR" term="%22Pilorget%2C+Corinne%22">Pilorget, Corinne</searchLink><br /><searchLink fieldCode="AR" term="%22Guizard%2C+Anne‐Valérie%22">Guizard, Anne‐Valérie</searchLink><br /><searchLink fieldCode="AR" term="%22Stücker%2C+Isabelle%22">Stücker, Isabelle</searchLink><br /><searchLink fieldCode="AR" term="%22Luce%2C+Danièle%22">Luce, Danièle</searchLink><br /><searchLink fieldCode="AR" term="%22for+the+Icare+Study+Group%22">for the Icare Study Group</searchLink> – Name: TitleSource Label: Source Group: Src Data: American Journal of Industrial Medicine; Oct2018, Vol. 61 Issue 10, p869-873, 5p – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22HEAD+%26+neck+cancer%22">HEAD & neck cancer</searchLink><br /><searchLink fieldCode="DE" term="%22SQUAMOUS+cell+carcinoma%22">SQUAMOUS cell carcinoma</searchLink><br /><searchLink fieldCode="DE" term="%22OCCUPATIONAL+hazards%22">OCCUPATIONAL hazards</searchLink><br /><searchLink fieldCode="DE" term="%22ALCOHOL+drinking%22">ALCOHOL drinking</searchLink><br /><searchLink fieldCode="DE" term="%22LOGISTIC+regression+analysis%22">LOGISTIC regression analysis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: To investigate the association between head and neck squamous cell cancer (HNSCC) risk and occupational exposure to flour dust in women and men, using data from ICARE, a French population‐based case‐control study. Methods: The analysis included 2053 cases of HNSCC and 3507 controls. Lifelong occupational history was collected. A job‐exposure matrix was used to assess exposure to flour dust. Odds‐ratios (ORs) and 95% confidence intervals (CI), adjusted for smoking, alcohol drinking, and asbestos exposure, were estimated with logistic regression models. Results: Ever exposure to flour dust was associated with elevated ORs in women (OR = 2.15, 95%CI: 1.01 4.55) and in men (OR = 1.55, 95%CI: 1.11 2.17). In women, the risk increased with the probability, the duration, and the cumulative level of exposure. No dose‐response relationships were observed in men. Conclusions: Although the results were less conclusive in men than in women, overall, these findings provide some support to the hypothesis of a role of flour dust in the occurrence of HNSCC. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of American Journal of Industrial Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/ajim.22899 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 869 Subjects: – SubjectFull: HEAD & neck cancer Type: general – SubjectFull: SQUAMOUS cell carcinoma Type: general – SubjectFull: OCCUPATIONAL hazards Type: general – SubjectFull: ALCOHOL drinking Type: general – SubjectFull: LOGISTIC regression analysis Type: general Titles: – TitleFull: Occupational exposure to flour dust and the risk of head and neck cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Carton, Matthieu – PersonEntity: Name: NameFull: Menvielle, Gwenn – PersonEntity: Name: NameFull: Cyr, Diane – PersonEntity: Name: NameFull: Sanchez, Marie – PersonEntity: Name: NameFull: Pilorget, Corinne – PersonEntity: Name: NameFull: Guizard, Anne‐Valérie – PersonEntity: Name: NameFull: Stücker, Isabelle – PersonEntity: Name: NameFull: Luce, Danièle – PersonEntity: Name: NameFull: for the Icare Study Group IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2018 Type: published Y: 2018 Identifiers: – Type: issn-print Value: 02713586 Numbering: – Type: volume Value: 61 – Type: issue Value: 10 Titles: – TitleFull: American Journal of Industrial Medicine Type: main |
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