Interaction of fructose with other medium components to affect bioproduction of docosahexaenoic acid (DHA) by Aurantiochytrium sp. SW1.

Bibliographic Details
Title: Interaction of fructose with other medium components to affect bioproduction of docosahexaenoic acid (DHA) by Aurantiochytrium sp. SW1.
Authors: Manikan, Vidyah, Kalil, Mohd. Sahaid, Shuib, Shuwahida, Hamid, Aidil Abdul, Ibrahim, Hanafiah, Jumali, Noorani, Hasbullah
Source: AIP Conference Proceedings; 2018, Vol. 1940 Issue 1, p1-1, 1p, 2 Charts, 2 Graphs
Subject Terms: THRAUSTOCHYTRIALES, FRUCTOSE, DOCOSAHEXAENOIC acid, MONOSODIUM glutamate, YEAST extract, MARINE fungi
Abstract: Thraustochytrids are a group of marine fungus-like microheterotrophs of which some can accumulate considerable amounts of the high valued omega-3 oil, docosahexaenoic acid (DHA). In this study, a local thraustochytrid isolate, Aurantiochytrium sp. SW1, was cultivated in a medium containing fructose as the major carbon source. The effects of this carbon source in interaction with yeast extract, monosodium glutamate (MSG) and sea salt were studied using a software-based two level full factorial design. Results showed that fructose as a single factor, has significant positive effect on the volumetric DHA content of SW1. Similarly, its interaction with yeast extract has profound positive effect. However, interactions of fructose with MSG and sea salt were significant negative effects. These results indicate that manipulation of the concentration of fructose in the culture medium may serve as a simple and useful strategy to help achieve preferred amount of DHA. [ABSTRACT FROM AUTHOR]
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Database: Complementary Index
More Details
ISSN:0094243X
DOI:10.1063/1.5027983
Published in:AIP Conference Proceedings
Language:English