Bibliographic Details
| Title: |
A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi. |
| Authors: |
Tabata Rosas-Diaz, Laura Medina-Puche, Li Tan, Heng Zhang, Weiman Xing, Shingo Nagawa, Dan Zhang, Pengfei Fan, Liping Wang, Xue Ding, Yuli Jiang, Tamara Jimenez-Gongora, Xinyan Zhao, Zhengyan Feng, Guiping Zhang, Jian-Kang Zhu, Rosa Lozano-Duran, Xiaokun Liu, Christine Faulkner, Bejarano, Eduardo R. |
| Source: |
Proceedings of the National Academy of Sciences of the United States of America; 2/6/2018, Vol. 115 Issue 6, p1388-1393, 6p |
| Subject Terms: |
RECEPTOR-like kinases, RNA interference, PLASMODESMATA, TOMATO yellow leaf curl virus, NICOTIANA benthamiana, VIRAL proteins, CELL membranes, PLANT cells & tissues |
| Abstract: |
RNA interference (RNAi) in plants can move from cell to cell, allowing for systemic spread of an antiviral immune response. How this cell-to-cell spread of silencing is regulated is currently unknown. Here, we describe that the C4 protein from Tomato yellow leaf curl virus can inhibit the intercellular spread of RNAi. Using this viral protein as a probe, we have identified the receptor-like kinase (RLK) BARELY ANY MERISTEM 1 (BAM1) as a positive regulator of the cell-to-cell movement of RNAi and determined that BAM1 and its closest homolog, BAM2, play a redundant role in this process. C4 interacts with the intracellular domain of BAM1 and BAM2 at the plasma membrane and plasmodesmata, the cytoplasmic connections between plant cells, interfering with the function of these RLKs in the cell-to-cell spread of RNAi. Our results identify BAM1 as an element required for the cell-to-cell spread of RNAi and highlight that signaling components have been coopted to play multiple functions in plants. [ABSTRACT FROM AUTHOR] |
|
Copyright of Proceedings of the National Academy of Sciences of the United States of America is the property of National Academy of Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Complementary Index |
