Bibliographic Details
| Title: |
Quality of 99mTcO4- from 99Mo Produced by 100Mo(n,2n)99Mo. |
| Authors: |
Yasuki Nagai, Yuto Nakahara, Masako Kawabata, Yuichi Hatsukawa, Kazuyuki Hashimoto, Hideya Saeki, Shoji Motoishi, Akio Ohta, Takayuki Shiina, Yukimasa Kawauchi |
| Source: |
Journal of the Physical Society of Japan; 2017, Vol. 86 Issue 5, p1-4, 4p |
| Abstract: |
The pharmaceutical quality of 99mTc pertechnetate solution obtained from 99Mo, the 100Mo(n,2n) reaction product, was investigated for the first time with an emphasis on the nonradioactive Mo content and endotoxin concentration. They were less than the tolerance dose given in international guidelines and the established upper limit in an international pharmacopoeia, respectively. Four other quality control tests commonly used for a commercially available 99mTc pertechnetate solution also demonstrated to meet the United States Pharmacopeia requirements. The results strongly support that the thermochromatographic separation method used to separate 99mTc from 99Mo can be a promising substitute for the fission product 99Mo. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
