Bibliographic Details
| Title: |
Extracorporeal shock wave therapy in the treatment of primary bone marrow edema syndrome of the knee: a prospective randomised controlled study. |
| Authors: |
Fuqiang Gao, Wei Sun, Zirong Li, Wanshou Guo, Weiguo Wang, Liming Cheng, Debo Yue, Nianfei Zhang, Savarin, Amanda, Gao, Fuqiang, Sun, Wei, Li, Zirong, Guo, Wanshou, Wang, Weiguo, Cheng, Liming, Yue, Debo, Zhang, Nianfei |
| Source: |
BMC Musculoskeletal Disorders; 12/5/2015, Vol. 16, p1-8, 8p, 2 Diagrams, 1 Chart, 3 Graphs |
| Subject Terms: |
EXTRACORPOREAL shock wave therapy, BONE marrow, KNEE injuries, LONGITUDINAL method, RANDOMIZED controlled trials, MAGNETIC resonance imaging, VISUAL analog scale, FOLLOW-up studies (Medicine), WOUNDS & injuries, DIAGNOSIS of edema, COMPARATIVE studies, BONE marrow diseases, EDEMA, HEALTH surveys, KNEE, LITHOTRIPSY, RESEARCH methodology, MEDICAL cooperation, QUESTIONNAIRES, RESEARCH, STATISTICAL sampling, SYNDROMES, EVALUATION research, PAIN measurement, TREATMENT effectiveness, DISEASE complications, DIAGNOSIS, THERAPEUTICS |
| Abstract: |
Background: The aim of this prospective study was to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in normalizing the symptoms and imaging features of primary bone marrow edema syndrome (BMES) of the knee.Methods: This study compared the outcomes of ESWT (Group A) (n = 20) and intravenously applied prostacyclin and bisphosphonate (Group B) (n = 20) in the treatment of BMES of the knee in our department between 2011 and 2013. The Visual Analog Scale for pain (VAS, 100 mm), the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), the SF-36 scores and MRI scans as well as plain radiographs were obtained before and after therapy between two groups.Results: Compared with Group B, we found greater improvement in VAS, the WOMAC Osteoarthritis Index and SF-36 score at 1, 3 and 6 months post-treatment in Group A (P < 0.05). Furthermore, MRI scans showed a higher incidence of distinct reduction and complete regression of bone marrow edema at 6 months in Group A (95 vs. 65 %; P = 0.018). The MRI at 1 year follow-up showed complete regression in all patients in Group A. However, two cases in Group B continued to normalize over the subsequent follow-up period.Conclusions: ESWT can produce rapid pain relief and functional improvement. It may be an effective, reliable, and non-invasive technique for rapid treatment of BMES of the knee.Trial Registration: Research Registry UIN 528, September 03, 2015. [ABSTRACT FROM AUTHOR] |
|
Copyright of BMC Musculoskeletal Disorders is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Complementary Index |
