Hot melt extrusion: enhancing the bioavailability of hydrophobic drugs.

Bibliographic Details
Title: Hot melt extrusion: enhancing the bioavailability of hydrophobic drugs.
Authors: Deshpande, Ameya1
Source: Manufacturing Chemist. Nov2021, Vol. 92 Issue 11, p24-26. 2p.
Subject Terms: *Extrusion process, Melt spinning, Drug bioavailability, Molecular weights, Ethylcellulose, Curcumin
Abstract: The article offers information on the active pharmaceutical ingredients (APis) with adequate aqueous solubility are formulated with a variety of components. It discusses that a lack of bioavailability is not the only concern when formulating a drug; developers must also consider the chemical stability of these compounds; and mentions that the enhanced bioavailability of an API means that a greater proportion of the active compound can reach a patient's systemic circulation.
Database: Business Source Complete
More Details
ISSN:02624230
Published in:Manufacturing Chemist
Language:English