Bibliographic Details
Title: |
Hot melt extrusion: enhancing the bioavailability of hydrophobic drugs. |
Authors: |
Deshpande, Ameya1 |
Source: |
Manufacturing Chemist. Nov2021, Vol. 92 Issue 11, p24-26. 2p. |
Subject Terms: |
*Extrusion process, Melt spinning, Drug bioavailability, Molecular weights, Ethylcellulose, Curcumin |
Abstract: |
The article offers information on the active pharmaceutical ingredients (APis) with adequate aqueous solubility are formulated with a variety of components. It discusses that a lack of bioavailability is not the only concern when formulating a drug; developers must also consider the chemical stability of these compounds; and mentions that the enhanced bioavailability of an API means that a greater proportion of the active compound can reach a patient's systemic circulation. |
Database: |
Business Source Complete |