Successful Polymyxin B Hemoperfusion Treatment Associated With Serial Reduction of Serum Anti-CADM-140/MDA5 Antibody Levels in Rapidly Progressive Interstitial Lung Disease With Amyopathic Dermatomyositis.

Bibliographic Details
Title: Successful Polymyxin B Hemoperfusion Treatment Associated With Serial Reduction of Serum Anti-CADM-140/MDA5 Antibody Levels in Rapidly Progressive Interstitial Lung Disease With Amyopathic Dermatomyositis.
Authors: Aoi Teruya1 tanaka.aoil0003@gmail.com, Kodai Kawamura1, Kazuya Ichikado1, Shinji Sato2, Yuko Yasuda1, Masakazu Yoshioka1
Source: CHEST. Dec2013, Vol. 144 Issue 6, p1934-1936. 3p.
Subject Terms: *LUNG diseases, *RESPIRATORY diseases, *DERMATOMYOSITIS, *ENZYME-linked immunosorbent assay, *HEMOPERFUSION, *IMMUNOGLOBULINS
Abstract: The article discusses the medical case of a 52-year-old man with rapidly progressive interstitial lung disease (RP-ILD) with clinically amyopathic dermatomyositis (CADM). The case showed the usefulness of determining the anti-CADM-140/MDA45 antibody levels by enzyme-linked immunosorbent assay to monitor the disease activity in patients with RP-ILD. Plymyxin-B direct hemoperfusion (PMX-DHP) helped reduce the antibody concentration.
Database: Academic Search Complete
More Details
ISSN:00123692
DOI:10.1378/chest.13-0186
Published in:CHEST
Language:English