Bibliographic Details
| Title: |
Turning up Francisella pathogenesis: The LPS thermostat. |
| Authors: |
Powell, Daniel A.1 (AUTHOR), Li, Yanyan2 (AUTHOR), Ernst, Robert K.1 (AUTHOR) rkernst@umaryland.edu |
| Source: |
Virulence. 11/15/2012, Vol. 3 Issue 7, p594-595. 3p. |
| Subject Terms: |
*FRANCISELLA novicida, *FATTY acid synthesis, *ACYLATION, *INTRACELLULAR pathogens, *ENZYMES |
| Abstract: |
The article discusses the role of thermal changes in outer membrane remodelling of the intracellular pathogens, Francisella novicida, in response to a comment by Y. Li et al. It is shown that lipid fatty acid composition in Francisella changes at both low and high temperature within the genetic and enzymatic levels. The N-linked acyltransferases, lpxD1 and lpxD2, are important in this changes because of their ability to catalyze acylation and preserve Francisella. |
| Database: |
Academic Search Complete |
|
Full text is not displayed to guests. |
Login for full access.
|
