| Title: |
Urticaria and Angioedema in Renal Cell Cancer Patients Treated with IL-2. |
| Authors: |
Logan, Theodore F.1 (AUTHOR), Strippoli, Giovanni2 (AUTHOR), Levine, Macy I.3 (AUTHOR) |
| Source: |
Cancer Investigation. Nov2007, Vol. 25 Issue 7, p584-588. 5p. 1 Black and White Photograph, 2 Charts. |
| Subject Terms: |
*INTERLEUKIN-2, *ERYTHEMA, *URTICARIA, *RENAL cell carcinoma, *SKIN tests, *ANAPHYLAXIS, *THERAPEUTICS |
| Abstract: |
Interleukin-2 therapy has produced significant improvement in a proportion of patients with renal cell cancer. Dermatologic side effects, such as erythema, have been very common. However, we could find only 2 reports of urticaria in the medical literature. Here, we report 8 patients with renal cell cancer who developed urticaria in association with interleukin-2 therapy. The hives tended to occur at the end of a treatment cycle. Skin tests with IL-2 were negative in two patients. Urticaria did not worsen or consistently occur with repeated courses of interleukin-2 and anaphylaxis was not observed in any patient. Six of the 8 patients previously had urticaria unrelated to IL-2 therapy. [ABSTRACT FROM AUTHOR] |
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