Bibliographic Details
| Title: |
Electromagnetic pulses induce fluctuations in blood pressure in rats. |
| Authors: |
Li, Bao-Feng1 (AUTHOR), Guo, Guo-Zhen1 (AUTHOR) Guozhen@fmmu.edu.cn, Ren, Dong-Qing1 (AUTHOR), Jing-Li1 (AUTHOR), Zhang, Ruo-Bing2 (AUTHOR) |
| Source: |
International Journal of Radiation Biology. Jun2007, Vol. 83 Issue 6, p421-429. 9p. 7 Graphs. |
| Subject Terms: |
*BLOOD pressure measurement, *HEART beat, *CARDIOVASCULAR system, *ELECTROMAGNETIC pulses, *LABORATORY rats |
| Abstract: |
Purpose: To investigate the effects of exposure to electromagnetic pulses (EMP) on functional indices of the cardiovascular system in male Sprague-Dawley rats. Materials and methods: A tapered parallel plate Gigahertz Transverse Electromagnetic cell (GTEM cell) with a flared rectangular coaxial transmission line was used to expose the rats to EMP (0.5 pps, total 200 pulses and whole-body averaged specific absorption rate 50 mW/kg at 200 kV/m or 75 mW/kg at 400 kV/m). Concurrent sham-exposed animals were used as controls. Cardiovascular functions, namely, heart rate, and systolic, mean and diastolic blood pressures were measured immediately and up to 4 weeks post-exposure using a non-invasive tail-cuff photoelectric sensor sphygmomanometer. Results: The heart rates in sham- and EMP-exposed rats were not significantly changed. In the exposed rats, increased systolic blood pressure (SBP) occurred at 0 h and decreased SBP occurred at 1 day and 3 days after exposure. Significantly higher diastolic blood pressure (DBP) was found at 0 h and significantly lower DBP was found at 12 h, 1 day, and 1 month after exposure. Significantly higher mean arterial pressure (MAP) was noted at 0 h and significantly lower MAP was noted at 1 day. Conclusions: Significant alterations in arterial blood pressure were observed in rats exposed to EMP exposure while heart rate was not altered. [ABSTRACT FROM AUTHOR] |
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