Bibliographic Details
| Title: |
Reference intervals for CD4 and hemoglobin among apparently healthy pregnant women in Addis Ababa, Ethiopia. |
| Authors: |
Chalchisa, Dinkenesh1 (AUTHOR) dinkeneshc@gmail.com, Belay, Yohannes1 (AUTHOR) yohab07@gmail.com, Kassaw, Melkitu2 (AUTHOR) kmelkitu@yahoo.com, Befekadu, Endalkachew3 (AUTHOR) endalkbestbefekadu@gmail.com, G/Egzeabher, Letebrhan4 (AUTHOR) ltsgbr@yahoo.com, Gebremicael, Gebremedhin1 (AUTHOR) kudus12@gmail.com, Lengiso, Boki1 (AUTHOR) bokilenjiso@gmail.com, Chala, Dawit1 (AUTHOR) dawitchala2016@gmail.com, Sahlemariam, Zewdineh5 (AUTHOR) zewdineh.sahlemariam@ju.edu.et, Kebede, Estifanos5 (AUTHOR) estifanos.kebede@ju.edu.et, Abate, Ebba6 (AUTHOR) ebbaabate@yahoo.com, Tsegaye, Aster7 (AUTHOR) tsegayeaster@yahoo.com |
| Source: |
BMC Research Notes. 3/11/2025, Vol. 18 Issue 1, p1-7. 7p. |
| Subject Terms: |
*CD4 lymphocyte count, *PREGNANT women, *CD4 antigen, *T cells, *HEMOGLOBINS |
| Geographic Terms: |
ETHIOPIA |
| Abstract: |
Background: Most African countries, including Ethiopia, have not developed local well-defined reference intervals (RIs) for immuno-hematological testes in terms of pregnant women. As a result, we were using reference intervals derived from non-Africans. This is not appropriate because CD4 + T cell counts (CD4 count) are affected by several factors including ethnic and environmental factors. Therefore, this study aimed to develop reference interval for CD4 count for apparently healthy pregnant women in Addis Ababa, Ethiopia. Results: After excluding six pregnant women who did not pass the screening tests, 156 apparently healthy pregnant women who were 18–49 years old were included in the final analysis. The medians of CD4 absolute counts and CD4% with inter-quartile ranges [IQR] were 757.5 [611.3-925.5] cells/µL and 43.6% [39.9–47.3] respectively while the median and IQR hemoglobin values were 14.3 g/dL [13.4–15.1]. The respective reference intervals for absolute CD4 cell count and % CD4 were 416.9-1218.4 cells/µL and 32.1–57.3%, respectively. Significant changes were observed in hemoglobin level between trimesters (P < 0.05). Conclusion: The results of this study showed a decrease in both percentage and absolute CD4 + T cell counts when compared to those of non-African and African countries. Establishing local reference values for diverse groups is therefore crucial. [ABSTRACT FROM AUTHOR] |
|
Copyright of BMC Research Notes is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Academic Search Complete |
|
Full text is not displayed to guests. |
Login for full access.
|
