| Title: |
Schmidt´s syndrome found by tan: a case report. |
| Authors: |
Venade, Gabriela1 gabivenade@hotmail.com, Almeida, Catarina1, Oliveira, Nídia1, Matos, Luis Costa1 |
| Source: |
Pan African Medical Journal. May-Aug2024, Vol. 48, p1-6. 6p. |
| Subject Terms: |
*ADDISON'S disease, *ADRENOCORTICOTROPIC hormone, *MEDICAL screening, *AUTOIMMUNE diseases, *HOSPITAL emergency services |
| Abstract: |
Addison´s disease can form part of type 2 autoimmune polyglandular syndrome. The article reports the case of a 41-year-old female patient with hypothyroidism and vitiligo, who came to the emergency department complaining of asthenia that had worsened in recent months, as well as anorexia, nausea, and weight loss (6 kg in a year). Cutaneous hyperpigmentation was the main finding on physical examination, together with vitiligo lesions on the face, hands, and armpits. Further study revealed a low serum cortisol level, normal urine-free cortisol, and an elevated adrenocorticotropic hormone (ACTH). Antiperoxidase antibodies and 17-alphahidroxylase antibodies were both positive. Treatment was started with prednisolone and fludrocortisone, and a good clinical response was obtained. This case report aims to draw attention to the high level of clinical suspicion required to diagnose Addison´s disease and the need to screen actively for other potentially associated autoimmune diseases that may be associated. [ABSTRACT FROM AUTHOR] |
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| Database: |
Academic Search Complete |
