| Title: |
Factors influencing rates of unsupervised assessment of short-term learning in cognitively unimpaired adults. |
| Authors: |
Lim, Yen Ying1,2,3 (AUTHOR) yenying.lim@monash.edu, Mills, Andrea1,4 (AUTHOR), Norfolk, Maya1,2 (AUTHOR), Rosenich, Emily1,2,3 (AUTHOR), Maruff, Paul2,3,5 (AUTHOR) |
| Source: |
Journal of Alzheimer's Disease. Jan2025, Vol. 103 Issue 2, p441-451. 11p. |
| Subject Terms: |
*LEARNING curve, *DISEASE risk factors, *OLDER people, *ALZHEIMER'S disease, *NEUROPSYCHOLOGICAL tests |
| Abstract: |
Background: In older adults with preclinical Alzheimer's disease (AD), learning curves derived from validated psychological learning paradigms are reduced to an extent greater than impairment, or decline, on neuropsychological memory tests. Objective: This study aimed to examine how age, sex, education, mood, and general dementia risk, which also increases risk for preclinical AD, could influence learning curves. Methods: 1050 adults enrolled in the BetterBrains trial completed 10 blocks of ORCA-LLT learning trials over 5 days. Learning curves were derived from improvement in accuracy over trials. Participants also completed questionnaires of demography and mood, and the CAIDE risk score was computed for each participant. Results: Most participants (67%) completed ≥6 blocks of ORCA-LLT. Older age (d = 0.75), lower education (d = 0.50), and higher dementia risk (d = 0.36) were associated significantly with slower learning rates. Conclusions: In older adults, learning curves are influenced subtly by age, education, and dementia risk but not by sex or mood. [ABSTRACT FROM AUTHOR] |
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| Database: |
Academic Search Complete |
