Bibliographic Details
| Title: |
Evaluation of Intrathecal Chloroprocaine Versus Bupivacaine in Adults for Perianal Surgeries. |
| Authors: |
Ahlawat, Mangal1 drmangalahlawat@gmail.com, Ahlawat, Geeta2 drgeetasaroha@gmail.com, Medhi, Sanjeev3 medhisanjeev99@gmail.com, Kshetrapal, Kirti4 kamalkirti47@gmail.com, bala, Renu4 neurodmrenu@gmail.com, Yadav, Tarun5 drtarunyadav@yahoo.com |
| Source: |
European Journal of Cardiovascular Medicine. 2024, Vol. 14 Issue 4, p469-476. 8p. |
| Subject Terms: |
*BUPIVACAINE, *TAMBAQUI, *ANESTHETICS, *RESEARCH protocols, *ANESTHESIA |
| Abstract: |
Introduction: Saddle anaesthesia is one of the prominent techniques of anaesthesia for perianal surgeries as it is straightforward with regard to procedure, economical and associated with minimal hemodynamic alteration. Perianal surgeries are often conducted as daycase procedures, commonly under saddle anaesthesia. However, the impact of selecting a specific local anaesthetic on relevant outcomes remains uncertain. We thought to investigate whether intra-thecal administration of 2-chloroprocaine would be associated with a enhanced recovery from central neuraxial block. Material and methods: In our study, eighty patients of either gender, 18- 65 years old, belonging to ASA physical status I – II, scheduled for perianal surgeries were included. Patients were randomly allocated into two groups using computer generated randomisation table. Group B (n=40) received 7.5 mg of 0.5 % of bupivacaine (hyperbaric). Group C (n=40) received 40 mg of 1% chloroprocaine (isobaric). The saddle block was administered as per the study protocol. Results: In our study we found that Chloroprocaine had a shorter sensory block duration than Bupivacaine (p <0.001) and we observed a shorter stay in PACU. The Chloroprocaine had a faster onset of motor block then Bupivacaine (p=0.001). The, Chloroprocaine had an earlier resolution of motor block, thus patient could ambulate earlier (p value= 0.001). TheVAS score and need for rescue analgesia was comparable up to the first 60 mins and then VAS score increased for the group receiving Chloroprocaine, showing that analgesia lasted up to 60 mins with Chloroprocaine while it is longer for Bupivacaine. Conclusion Chloroprocaine and Bupivacaine are both useful drugs for providing saddle block for doing perianal surgeries. Chloroprocaine is a good alternative to the time-tested Bupivacaine, as it has an advantage of slight early onset, attains adequate level of sensory block, for a shorter duration, and regresses faster thus reducing stay in PACU. Moreover, it has the advantage of early onset and rapid regression of motor block and thus patients can ambulate earlier. Therefore, chloroprocaine can be recommended for saddle block in perianal surgeries of short duration. [ABSTRACT FROM AUTHOR] |
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