| Title: |
Influence of Epilepsy Characteristics on the Anxiety Occurrence. |
| Authors: |
Gavrilovic, Aleksandar1,2 (AUTHOR) aleksandar.gavrilovic@fmn.kg.ac.rs, Gavrilovic, Jagoda3,4 (AUTHOR) jagoda.gavrilovic@fmn.kg.ac.rs, Ilic Zivojinovic, Jelena5 (AUTHOR) jelena.ilic-zivojinovic@med.bg.ac.rs, Jeličić, Ljiljana6,7 (AUTHOR) lj.jelicic@add-for-life.com, Radovanovic, Snezana8 (AUTHOR) snezana.radovanovic@fmn.kg.ac.rs, Vesic, Katarina1,2 (AUTHOR) katarina.vesic@fmn.kg.ac.rs |
| Source: |
Brain Sciences (2076-3425). Sep2024, Vol. 14 Issue 9, p858. 11p. |
| Subject Terms: |
*PEOPLE with epilepsy, *DRUG resistance, *ANXIETY, *THERAPEUTICS, *QUALITY of life |
| Abstract: |
The presence of anxiety in individuals with epilepsy significantly influences their medical treatment and quality of life and often goes unrecognized or untreated, posing a challenge to differential diagnosis. The study aimed to investigate the influence of epilepsy characteristics on anxiety. The research involved 155 patients with generalized and focal drug-sensitive [DSE] and drug-resistant [DRE] epilepsy. Hamilton anxiety rating scale [HAS] was used to assess the symptoms of anxiety at three time points [baseline, 12, and 18 months]. DSE patients exhibited significantly lower HAM-A scores than patients with DRE at the initial visit [p = 0.000] after 12 [p = 0.000] and 18-month follow-up [p = 0.000]. Focal DRE patients presented higher HAM-A scores than focal DSE patients in the initial visit [p = 0.000] after 12 [p = 0.000] and 18 months [p = 0.000]. Medication responsiveness, seizure type, and illness duration emerged as significant anxiety predictors [p = 0.000]. After 18 months of follow-up, significant contributors to anxiety were drug responsivity and illness duration [p = 0.000]. The occurrence of anxiety in epilepsy patients is most significantly influenced by well-controlled epilepsy and a positive response to medication. [ABSTRACT FROM AUTHOR] |
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