Contrast-Induced Encephalopathy: A Case Series Analysis.

Bibliographic Details
Title: Contrast-Induced Encephalopathy: A Case Series Analysis.
Authors: Stebner, Alexander1,2,3, Bosshart, Salome1,2, Hainc, Nicolin4, Nierobisch, Nathalie4, Zedde, Marialuisa5, Pascarella, Rosario5, Goyal, Mayank1,2, Ospel, Johanna1,2 johannaospel@gmail.com
Source: Annals of Indian Academy of Neurology. Jul/Aug2024, Vol. 27 Issue 4, p403-407. 5p.
Subject Terms: *IODINE radioisotopes, *RESEARCH funding, *ENDOVASCULAR aneurysm repair, *COMPUTED tomography, *BRAIN diseases, *ENDOVASCULAR surgery, *PREDNISOLONE, *RETROSPECTIVE studies, *CASE studies, *CORONARY angiography
Abstract: Background: Contrast-induced encephalopathy (CIE) is a rare adverse event linked to intravascular use of iodine-containing contrast media. The prevalence of CIE could increase in the future due to growing numbers of endovascular procedures. We provide insights from a case series of 7 patients. Methods: Cases from 3 centers were collected based on existing academic collaborations, and key factors were extracted to illustrate development and management of CIE. Results: In our retrospective case-series analysis of 7 cases from 3 countries, affected patients had an equal distribution of sex (4 women, 3 men) and a median age of 75 (IQR 63-77). Common risk factors included hypertension (5/7), hyperlipidemia (5/7), previous stroke (3/7), and type 2 diabetes (3/7). CIE developed in 3 cases after endovascular thrombectomy (EVT) for stroke, in 2 cases after aneurysm treatment, in 1 case after cardiac catheterization, and in 1 case after diagnostic computed tomography (CT) angiography without an endovascular procedure. The median procedure time was 48 min (IQR 40-81). All patients received non-ionic, low-osmolar contrast agents with volumes ranging from 100-300 ml. Symptom onset was close to contrast administration, with stroke-like neurological deficits being most common (4/7). Prednisolone was the most frequently used medication to treat the symptoms (4/7). Symptom resolution occurred in 4 out of 7 patients within two to several days, and 1 patient died, but without clear connection to CIE. Conclusion: CIE is a rare and possibly underrecognized condition, but fortunately, with a favorable outcome in most cases. [ABSTRACT FROM AUTHOR]
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Database: Academic Search Complete
More Details
ISSN:09722327
DOI:10.4103/aian.aian_548_24
Published in:Annals of Indian Academy of Neurology
Language:English