Bibliographic Details
| Title: |
Tobacco‐enhanced biofilm formation by Porphyromonas gingivalis and other oral microbes. |
| Authors: |
Tan, Jinlian1 (AUTHOR), Lamont, Gwyneth J.1 (AUTHOR), Scott, David A.1,2 (AUTHOR) david.scott@louisville.edu |
| Source: |
Molecular Oral Microbiology. Oct2024, Vol. 39 Issue 5, p270-290. 21p. |
| Subject Terms: |
*BACTERIAL physiology, *DYSBIOSIS, *MICROORGANISMS, *PERIODONTITIS, *TOBACCO, *BIOFILMS |
| Abstract: |
Microbial biofilms promote pathogenesis by disguising antigens, facilitating immune evasion, providing protection against antibiotics and other antimicrobials and, generally, fostering survival and persistence. Environmental fluxes are known to influence biofilm formation and composition, with recent data suggesting that tobacco and tobacco‐derived stimuli are particularly important mediators of biofilm initiation and development in vitro and determinants of polymicrobial communities in vivo. The evidence for tobacco‐augmented biofilm formation by oral bacteria, tobacco‐induced oral dysbiosis, tobacco‐resistance strategies, and bacterial physiology is summarized herein. A general overview is provided alongside specific insights gained through studies of the model and archetypal, anaerobic, Gram‐negative oral pathobiont, Porphyromonas gingivalis. [ABSTRACT FROM AUTHOR] |
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| Database: |
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