Bibliographic Details
Title: |
Molecular image–guided surgery in gynaecological cancer: where do we stand? |
Authors: |
Pisano, Giusi1 (AUTHOR), Wendler, Thomas2,3 (AUTHOR), Valdés Olmos, Renato A.4 (AUTHOR), Garganese, Giorgia5,6 (AUTHOR), Rietbergen, Daphne D. D.4 (AUTHOR), Giammarile, Francesco7 (AUTHOR), Vidal-Sicart, Sergi8 (AUTHOR), Oonk, Maaike H. M.9 (AUTHOR), Frumovitz, Michael10 (AUTHOR), Abu-Rustum, Nadeem R.11 (AUTHOR), Scambia, Giovanni5,6 (AUTHOR), Rufini, Vittoria1,12 (AUTHOR), Collarino, Angela12 (AUTHOR) angela.collarino@policlinicogemelli.it |
Source: |
European Journal of Nuclear Medicine & Molecular Imaging. Aug2024, Vol. 51 Issue 10, p3026-3039. 14p. |
Subject Terms: |
*TECHNOLOGICAL innovations, *COMPUTER-assisted surgery, *SENTINEL lymph nodes, *CLINICAL medicine, *THREE-dimensional imaging, *SURGICAL robots |
Abstract: |
Purpose: The aim of this review is to give an overview of the current status of molecular image–guided surgery in gynaecological malignancies, from both clinical and technological points of view. Methods: A narrative approach was taken to describe the relevant literature, focusing on clinical applications of molecular image–guided surgery in gynaecology, preoperative imaging as surgical roadmap, and intraoperative devices. Results: The most common clinical application in gynaecology is sentinel node biopsy (SNB). Other promising approaches are receptor-target modalities and occult lesion localisation. Preoperative SPECT/CT and PET/CT permit a roadmap for adequate surgical planning. Intraoperative detection modalities span from 1D probes to 2D portable cameras and 3D freehand imaging. Conclusion: After successful application of radio-guided SNB and SPECT, innovation is leaning towards hybrid modalities, such as hybrid tracer and fusion of imaging approaches including SPECT/CT and PET/CT. Robotic surgery, as well as augmented reality and virtual reality techniques, is leading to application of these innovative technologies to the clinical setting, guiding surgeons towards a precise, personalised, and minimally invasive approach. [ABSTRACT FROM AUTHOR] |
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Database: |
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