Arrhythmias and ion channelopathies causing sudden cardiac death in Hispanic/Latino and Indigenous populations.

Bibliographic Details
Title: Arrhythmias and ion channelopathies causing sudden cardiac death in Hispanic/Latino and Indigenous populations.
Authors: Zaveri, Sahil1,2, Chahine, Mohamed3,4, Boutjdir, Mohamed1,2,5 mohamed.boutjdir@va.gov
Source: Journal of Cardiovascular Electrophysiology. Jun2024, Vol. 35 Issue 6, p1219-1228. 10p.
Subject Terms: *ARRHYTHMIA diagnosis, *ARRHYTHMIA prevention, *RISK assessment, *MEDICAL quality control, *HISPANIC Americans, *INDIGENOUS peoples, *SOCIOECONOMIC factors, *GENETIC variation, *ARRHYTHMIA, *PATHOGENESIS, *CARDIAC arrest, *HEALTH equity, *DISEASE susceptibility, *ION channels, *PSYCHOSOCIAL factors, *DISEASE risk factors, *DISEASE complications
Geographic Terms: UNITED States
Abstract: The limited literature and increasing interest in studies on cardiac electrophysiology, explicitly focusing on cardiac ion channelopathies and sudden cardiac death in diverse populations, has prompted a comprehensive examination of existing research. Our review specifically targets Hispanic/Latino and Indigenous populations, which are often underrepresented in healthcare studies. This review encompasses investigations into genetic variants, epidemiology, etiologies, and clinical risk factors associated with arrhythmias in these demographic groups. The review explores the Hispanic paradox, a phenomenon linking healthcare outcomes to socioeconomic factors within Hispanic communities in the United States. Furthermore, it discusses studies exemplifying this observation in the context of arrhythmias and ion channelopathies in Hispanic populations. Current research also sheds light on disparities in overall healthcare quality in Indigenous populations. The available yet limited literature underscores the pressing need for more extensive and comprehensive research on cardiac ion channelopathies in Hispanic/Latino and Indigenous populations. Specifically, additional studies are essential to fully characterize pathogenic genetic variants, identify population‐specific risk factors, and address health disparities to enhance the detection, prevention, and management of arrhythmias and sudden cardiac death in these demographic groups. [ABSTRACT FROM AUTHOR]
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ISSN:10453873
DOI:10.1111/jce.16282
Published in:Journal of Cardiovascular Electrophysiology
Language:English