Long non‐coding RNAs as promising targets for controlling disease vector mosquitoes.

Bibliographic Details
Title: Long non‐coding RNAs as promising targets for controlling disease vector mosquitoes.
Authors: Han, Yujiao1 (AUTHOR), Pu, Qian1 (AUTHOR), Fan, Ting1 (AUTHOR), Wei, Tianqi1 (AUTHOR), Xu, Yankun1 (AUTHOR), Zhao, Lu1 (AUTHOR), Liu, Shiping1 (AUTHOR) lsp98668@163.com
Source: Insect Science. May2024, p1. 18p. 4 Illustrations.
Abstract: Hematophagous female mosquitoes are important vectors of numerous devastating human diseases, posing a major public health threat. Effective prevention and control of mosquito‐borne diseases rely considerably on progress in understanding the molecular mechanisms of various life activities, and accordingly, the molecules that regulate the various life activities of mosquitoes are potential targets for implementing future vector control strategies. Many long non‐coding RNAs (lncRNAs) have been identified in mosquitoes and significant progress has been made in determining their functions. Here, we present a comprehensive overview of the research advances on mosquito lncRNAs, including their molecular identification, function, and interaction with other non‐coding RNAs, as well as their synergistic regulatory roles in mosquito life activities. We also highlight the potential roles of competitive endogenous RNAs in mosquito growth and development, as well as in insecticide resistance and virus–host interactions. Insights into the biological functions and mechanisms of lncRNAs in mosquito life activities, viral replication, pathogenesis, and transmission will contribute to the development of novel drugs and safe vaccines. [ABSTRACT FROM AUTHOR]
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Database: Academic Search Complete
More Details
ISSN:16729609
DOI:10.1111/1744-7917.13383
Published in:Insect Science
Language:English