| Title: |
Case Report: Life-Threatening Fluoxetine-Linked Postoperative Bleeding Informed by Pharmacogenetic Evaluation. |
| Authors: |
Rogers, Sara1,2,3,4 (AUTHOR) sararogers@tamu.edu, Silva, Patrick J.2,3 (AUTHOR), Udeani, George1,2,3 (AUTHOR), Deleon, Monica1 (AUTHOR), Mutyala, Sriarchala1 (AUTHOR), Panahi, Ladan1 (AUTHOR), Abu-Baker, Asim1 (AUTHOR), Neal, Gabriel5 (AUTHOR), Ramos, Kenneth S.2,3 (AUTHOR) |
| Source: |
Drugs in R&D. Mar2024, Vol. 24 Issue 1, p117-121. 5p. |
| Subject Terms: |
*SEROTONIN uptake inhibitors, *ANTIDEPRESSANTS, *SEROTONIN, *HEMORRHAGE |
| Abstract: |
Background: Selective serotonin reuptake inhibitors (SSRI) are commonly used for the treatment of depression and anxiety. Inhibition of serotonin reuptake in platelets increases bleeding risk in patients taking SSRIs. Case: Here, we present the case of a 52-year-old patient who developed severe postsurgical bleeding requiring blood transfusion following panniculectomy. Conclusion: SSRI-induced bleeding is dose-related and strongly influenced by individual variations in drug metabolizing enzymes and transporters. BJYwPVEYn-uvqVov7uRYgK Supplementary file1 (MP4 8441 KB) [ABSTRACT FROM AUTHOR] |
|
Copyright of Drugs in R&D is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Academic Search Complete |
|
Full text is not displayed to guests. |
Login for full access.
|
