Bibliographic Details
| Title: |
Hyaluronan: Sources, Structure, Features and Applications. |
| Authors: |
Valachová, Katarína1 (AUTHOR) katarina.valachova@savba.sk, Hassan, Mohamed E.1,2 (AUTHOR), Šoltés, Ladislav1 (AUTHOR) |
| Source: |
Molecules. Feb2024, Vol. 29 Issue 3, p739. 15p. |
| Subject Terms: |
*HYALURONIC acid, *GLYCOSAMINOGLYCANS, *MEDICAL polymers, *NANOMEDICINE, *MOLAR mass, *ORGANS (Anatomy), *MEDICAL practice |
| Abstract: |
Hyaluronan (HA) is a non-sulfated glycosaminoglycan that is present in a variety of body tissues and organs. Hyaluronan has a wide range of biological activities that are frequently influenced by molar mass; however, they also depend greatly on the source, purity, and kind of impurities in hyaluronan. High-molar-mass HA has anti-inflammatory, immunosuppressive, and antiangiogenic properties, while low-molar-mass HA has opposite properties. A number of chemical modifications have been performed to enhance the stability of HA and its applications in medical practice. Hyaluronan is widely applied in medicine, such as viscosupplementation, ophthalmology, otolaryngology, wound healing, cosmetics, and drug delivery. In this review, we summarized several medical applications of polymers based on the hyaluronan backbone. [ABSTRACT FROM AUTHOR] |
|
Copyright of Molecules is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Academic Search Complete |
|
Full text is not displayed to guests. |
Login for full access.
|
