Bibliographic Details
| Title: |
Recent Advances in Asymmetric Synthesis of Chiral Cyclobutenes. |
| Authors: |
Hu, Fangdong1 (AUTHOR), Zhao, Yueting1 (AUTHOR), Che, Lin1 (AUTHOR), Yan, Xufei2 (AUTHOR) yanxf92@scu.edu.cn, Xia, Ying2 (AUTHOR) xiayingscu@scu.edu.cn |
| Source: |
ChemCatChem. Feb2024, Vol. 16 Issue 3, p1-22. 22p. |
| Subject Terms: |
*ASYMMETRIC synthesis, *CYCLOBUTENES, *NATURAL products, *BIOACTIVE compounds, *RING formation (Chemistry) |
| Abstract: |
Cyclobutene scaffolds occur in natural products and bioactive compounds. Their unique structural features and intrinsic ring strain make cyclobutene a type of important building block in synthetic chemistry. In recent years, considerable efforts have been dedicated to the synthesis of chiral cyclobutenes. Enantioselective [2+2] cycloadditions and functionalization of cyclobutene derivatives have emerged as powerful and reliable protocols for achieving this goal, resulting in significant progress in this field. This review provides a comprehensive summary of the recent advancements in the asymmetric synthesis of chiral cyclobutenes, and the discussion is logically divided into four parts according to the reaction mode. [ABSTRACT FROM AUTHOR] |
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