| Title: |
Measuring Absolute Coronary Flow and Microvascular Resistance by Thermodilution: JACC Review Topic of the Week. |
| Authors: |
Belmonte, Marta1,2 (AUTHOR), Gallinoro, Emanuele1,3 (AUTHOR), Pijls, Nico H.J.1,4 (AUTHOR) nico.pijls@xs4all.nl, Bertolone, Dario Tino1 (AUTHOR), Keulards, Danielle C.J.4,5 (AUTHOR), Viscusi, Michele Mattia1,2 (AUTHOR), Storozhenko, Tatyana1 (AUTHOR), Mizukami, Takuya1 (AUTHOR), Mahendiran, Thabo1,6 (AUTHOR), Seki, Ruiko1 (AUTHOR), Fournier, Stephane6 (AUTHOR), de Vos, Annemiek4,5 (AUTHOR), Adjedj, Julien7 (AUTHOR), Barbato, Emanuele8 (AUTHOR), Sonck, Jeroen1 (AUTHOR), Damman, Peter9 (AUTHOR), Keeble, Thomas10,11 (AUTHOR), Fawaz, Samer10,11 (AUTHOR), Gutiérrez-Barrios, Alejandro12,13 (AUTHOR), Paradies, Valeria14 (AUTHOR) |
| Source: |
Journal of the American College of Cardiology (JACC). Feb2024, Vol. 83 Issue 6, p699-709. 11p. |
| Subject Terms: |
*CORONARY circulation, *BLOOD flow measurement, *FLOW measurement, *MICROCIRCULATION disorders, *MICROCIRCULATION |
| Abstract: |
Diagnosing coronary microvascular dysfunction remains challenging, primarily due to the lack of direct measurements of absolute coronary blood flow (Q) and microvascular resistance (R μ). However, there has been recent progress with the development and validation of continuous intracoronary thermodilution, which offers a simplified and validated approach for clinical use. This technique enables direct quantification of Q and R μ , leading to precise and accurate evaluation of the coronary microcirculation. To ensure consistent and reliable results, it is crucial to follow a standardized protocol when performing continuous intracoronary thermodilution measurements. This document aims to summarize the principles of thermodilution-derived absolute coronary flow measurements and propose a standardized method for conducting these assessments. The proposed standardization serves as a guide to ensure the best practice of the method, enhancing the clinical assessment of the coronary microcirculation. [Display omitted] • Diagnosis of coronary microcirculatory dysfunction requires measurement of coronary blood flow and microvascular resistance. • Absolute coronary blood flow and microvascular resistance can be accurately measured by means of continuous intracoronary thermodilution. • This paper proposes a standardized protocol to perform these measurements. [ABSTRACT FROM AUTHOR] |
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| Database: |
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