Lithium as an alternative option in thionamide-resistant Graves' disease.

Bibliographic Details
Title: Lithium as an alternative option in thionamide-resistant Graves' disease.
Authors: Ying Ki Chung1 cyk474@ha.org.hk, Lap Ming Wong2
Source: Clinical Pediatric Endocrinology. Jul2023, Vol. 32 Issue 3, p168-173. 6p.
Subject Terms: *GRAVES' disease, *IODINE isotopes, *TEENAGE girls, *LITHIUM carbonate, *TREATMENT effectiveness
Abstract: Conventional treatments for Graves' disease include thionamides, radioactive iodine therapy (RAI), and thyroidectomy. Occasionally, patients may develop resistance to thionamides and may require additional treatment. We present the case of an adolescent girl with thionamide-resistant Graves' disease who was successfully treated with lithium and subsequent RAI after stabilizing her thyroid hormone levels. Following RAI, the patient developed hypothyroidism, and thyroxine replacement therapy was initiated. This case highlights the potential of lithium as a safe and effective alternative for controlling hyperthyroidism in Graves' disease and its role in preparing patients for more definitive treatment. [ABSTRACT FROM AUTHOR]
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  Label: Title
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  Data: Lithium as an alternative option in thionamide-resistant Graves' disease.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Ying+Ki+Chung%22">Ying Ki Chung</searchLink><relatesTo>1</relatesTo><i> cyk474@ha.org.hk</i><br /><searchLink fieldCode="AR" term="%22Lap+Ming+Wong%22">Lap Ming Wong</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Clinical+Pediatric+Endocrinology%22">Clinical Pediatric Endocrinology</searchLink>. Jul2023, Vol. 32 Issue 3, p168-173. 6p.
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: *<searchLink fieldCode="DE" term="%22GRAVES'+disease%22">GRAVES' disease</searchLink><br />*<searchLink fieldCode="DE" term="%22IODINE+isotopes%22">IODINE isotopes</searchLink><br />*<searchLink fieldCode="DE" term="%22TEENAGE+girls%22">TEENAGE girls</searchLink><br />*<searchLink fieldCode="DE" term="%22LITHIUM+carbonate%22">LITHIUM carbonate</searchLink><br />*<searchLink fieldCode="DE" term="%22TREATMENT+effectiveness%22">TREATMENT effectiveness</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Conventional treatments for Graves' disease include thionamides, radioactive iodine therapy (RAI), and thyroidectomy. Occasionally, patients may develop resistance to thionamides and may require additional treatment. We present the case of an adolescent girl with thionamide-resistant Graves' disease who was successfully treated with lithium and subsequent RAI after stabilizing her thyroid hormone levels. Following RAI, the patient developed hypothyroidism, and thyroxine replacement therapy was initiated. This case highlights the potential of lithium as a safe and effective alternative for controlling hyperthyroidism in Graves' disease and its role in preparing patients for more definitive treatment. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Clinical Pediatric Endocrinology is the property of Japanese Society for Pediatric Endocrinology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1297/cpe.2022-0070
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      – Code: eng
        Text: English
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        PageCount: 6
        StartPage: 168
    Subjects:
      – SubjectFull: GRAVES' disease
        Type: general
      – SubjectFull: IODINE isotopes
        Type: general
      – SubjectFull: TEENAGE girls
        Type: general
      – SubjectFull: LITHIUM carbonate
        Type: general
      – SubjectFull: TREATMENT effectiveness
        Type: general
    Titles:
      – TitleFull: Lithium as an alternative option in thionamide-resistant Graves' disease.
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            NameFull: Ying Ki Chung
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            NameFull: Lap Ming Wong
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            – D: 01
              M: 07
              Text: Jul2023
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              Y: 2023
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              Value: 32
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            – TitleFull: Clinical Pediatric Endocrinology
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