Lithium as an alternative option in thionamide-resistant Graves' disease.

Bibliographic Details
Title: Lithium as an alternative option in thionamide-resistant Graves' disease.
Authors: Ying Ki Chung1 cyk474@ha.org.hk, Lap Ming Wong2
Source: Clinical Pediatric Endocrinology. Jul2023, Vol. 32 Issue 3, p168-173. 6p.
Subject Terms: *GRAVES' disease, *IODINE isotopes, *TEENAGE girls, *LITHIUM carbonate, *TREATMENT effectiveness
Abstract: Conventional treatments for Graves' disease include thionamides, radioactive iodine therapy (RAI), and thyroidectomy. Occasionally, patients may develop resistance to thionamides and may require additional treatment. We present the case of an adolescent girl with thionamide-resistant Graves' disease who was successfully treated with lithium and subsequent RAI after stabilizing her thyroid hormone levels. Following RAI, the patient developed hypothyroidism, and thyroxine replacement therapy was initiated. This case highlights the potential of lithium as a safe and effective alternative for controlling hyperthyroidism in Graves' disease and its role in preparing patients for more definitive treatment. [ABSTRACT FROM AUTHOR]
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Database: Academic Search Complete
More Details
ISSN:09185739
DOI:10.1297/cpe.2022-0070
Published in:Clinical Pediatric Endocrinology
Language:English