Analysis of the Differences in Ocular Surface Damage and Inflammatory Signs between Healthy and Evaporative Dry Eye Participants.

Bibliographic Details
Title: Analysis of the Differences in Ocular Surface Damage and Inflammatory Signs between Healthy and Evaporative Dry Eye Participants.
Authors: Garcia-Queiruga, Jacobo1 (AUTHOR) jacobogarcia.queiruga@usc.es, Pena-Verdeal, Hugo1 (AUTHOR), Sabucedo-Villamarin, Belén1 (AUTHOR), Garcia-Resua, Carlos1 (AUTHOR), Giraldez, Maria J.1 (AUTHOR), Yebra-Pimentel, Eva1 (AUTHOR)
Source: Ocular Immunology & Inflammation. Jul2023, Vol. 31 Issue 5, p970-977. 8p.
Subject Terms: *DRY eye syndromes, *HYPEREMIA, *EYE diseases, *CORNEA, *MEIBOMIAN glands
Abstract: Distinguish between EDE severity levels by analysing the MGLA, conjunctival hyperemia and corneal staining. One hundred participants were recruited based on OSDI, TO, TFBUT, TMH, and LLP to be categorised as healthy (Group 1) or EDE (Group 2). Group 2 was divided into Group 2A (mild symptoms), 2B (moderate), and 2C (severe). MGLA, conjunctival hyperemia, and corneal staining were measured. Positive correlation between MGLA, conjunctival hyperemia, and corneal staining were found (all r ≥ 0.221, p ≤ 0.027). Significant differences were found: MGLA between Group 1 vs. 2C and 2C vs. 2A or 2B; conjunctival hyperemia between Group 1 vs. 2A, 2B or 2C; corneal staining between Group 1 vs. 2B or 2C and 2A vs. 2B or 2C (all p ≤ 0.049). Severe EDE participants have higher MGLA, conjunctival hyperemia, and corneal staining values than healthy, mild, or moderate EDE participants. [ABSTRACT FROM AUTHOR]
Copyright of Ocular Immunology & Inflammation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Academic Search Complete
Full text is not displayed to guests.
More Details
ISSN:09273948
DOI:10.1080/09273948.2022.2075398
Published in:Ocular Immunology & Inflammation
Language:English