Bibliographic Details
| Title: |
Pachymetric Assessment After EpiSmart® Epithelium-on Cross-Linking for Keratoconus and Post-Surgical Ectasia. |
| Authors: |
Vaidya, Neel S (AUTHOR), Daneshmand, Arvin (AUTHOR), Epstein, Randy J (AUTHOR), Majmudar, Parag A (AUTHOR), Belin, Michael W (AUTHOR), Parsons, Edward C (AUTHOR), Rubinfeld, Roy S (AUTHOR) |
| Source: |
Clinical Ophthalmology. Jun2022, Vol. 16, p1829-1835. 7p. |
| Subject Terms: |
*KERATOCONUS, *CORNEA |
| Abstract: |
Purpose: To assess the change in corneal pachymetry after a novel epithelium-on (EpiSmart®) corneal crosslinking procedure (CXL). Methods: Eyes treated as part of the open-label, non-controlled arm of the study "Collagen Crosslinking with Ultraviolet-A in Asymmetric Corneas" (NCT01097447) were examined at baseline, 3-, 6- and 12-months post-CXL. Thinnest pachymetry readings based on Pentacam (OCULUS GmbH, Wetzlar, Germany) were recorded. Results: A total of 101 eyes met the study inclusion criteria. Thinnest pachymetric readings at baseline averaged 451 ± 50 microns. The mean (± SD) minimum thickness was 450 ± 46 microns at 3 months, 452 ± 47 microns at 6 months, and 451 ± 48 microns at 12 months post-CXL. The changes from baseline (mean ± SE) at 3, 6, and 12 months post-CXL were − 1.2 ± 1.5 microns, 0.5 ± 1.6 microns, and 0.4 ± 1.6 microns, respectively. Student's t-tests showed no statistically significant change in pachymetry from baseline for any exam period. Conclusion: This study demonstrated that, after EpiSmart® epithelium-on CXL, there was no substantial corneal thinning observable on Scheimpflug tomography out to 12 months. [ABSTRACT FROM AUTHOR] |
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| Database: |
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