Bibliographic Details
| Title: |
Lowering the setting value of the esophageal endoscopic submucosal dissection device enabled tissue damage control in vitro porcine model. |
| Authors: |
Yamaguchi, Yukiko1 (AUTHOR), Uesato, Masaya1 (AUTHOR) uesato@faculty.chiba-u.jp, Yonemoto, Shohei1 (AUTHOR), Maruyama, Tetsuro1 (AUTHOR), Urahama, Ryuma1 (AUTHOR), Suito, Hiroshi1 (AUTHOR), Kishimoto, Takashi2 (AUTHOR), Shiko, Yuki3 (AUTHOR), Ozawa, Yoshihito3 (AUTHOR), Kawasaki, Yohei3 (AUTHOR), Matsubara, Hisahiro1 (AUTHOR) |
| Source: |
Scientific Reports. 2/23/2022, Vol. 12 Issue 1, p1-7. 7p. |
| Subject Terms: |
*WIND damage, *TEMPERATURE effect, *DISSECTION, *HIGH temperatures, *ESOPHAGUS |
| Abstract: |
One of the complications of esophageal endoscopic submucosal dissection (ESD) is postoperative stricture formation. Stenosis formation is associated with inflammation and fibrosis in the healing process. We hypothesized that the degree of thermal damage caused by the device is related to stricture formation. We aimed to reveal the relationship between thermal damage and setting value of the device. We energized a resected porcine esophagus using the ESD device (Flush Knife 1.5). We performed 10 energization points for 1 s, 3 s, and 5 s at four setting values of the device. We measured the amount of current flowing to the conducted points and the temperature and evaluated the effects of thermal damage pathologically. As results, the mean highest temperatures for 1 s were I (SWIFT Effect3 Wat20): 61.19 °C, II (SWIFT Effect3 Wat30): 77.28 °C, III (SWIFT Effect4 Wat20): 94.50 °C, and IV (SWIFT Effect4 Wat30): 94.29 °C. The mean heat denaturation areas were I: 0.84 mm2, II: 1.00 mm2, III: 1.91 mm2, and IV: 1.54 mm2. The mean highest temperature and mean heat denaturation area were significantly correlated (P < 0.001). In conclusion, Low-current ESD can suppress the actual temperature and thermal damage in the ESD wound. [ABSTRACT FROM AUTHOR] |
|
Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Academic Search Complete |
|
Full text is not displayed to guests. |
Login for full access.
|
