Bibliographic Details
| Title: |
Corneal Crosslinking Biomechanics Evaluated by a Novel and Easily Implemented Differential Tonometry Method. |
| Authors: |
Wang, Mingwu1 (AUTHOR), Berdahl, John2 (AUTHOR), McCafferty, Sean3 (AUTHOR) SJMccafferty66@hotmail.com |
| Source: |
Current Eye Research. November 2021, Vol. 46 Issue 11, p1614-1620. 7p. |
| Subject Terms: |
*CORNEA, *TONOMETRY, *BIOMECHANICS, *INTRAOCULAR pressure, *UNITS of measurement, *PRISMS |
| Abstract: |
Purpose: Evaluate potential corneal biomechanical changes following corneal crosslinking (CXL) by paired differential tonometry intraocular pressure (IOP) measurements with a Goldmann tonometer (GAT) prism and corneal compensating, correcting applanation tonometry surface (CATS) prism. Methods: IOP was measured prospectively on 23 unique eyes undergoing CXL for keratoconus with a GAT using a standard flat GAT prism and a curved corneal error correcting CATS prism before treatment and at 2 weeks, 2 months and 6 months after treatment. Concurrent measurements of central corneal thickness (CCT) and corneal hysteresis (CH) were completed. Results: Paired IOP measurements with standard GAT and corneal correcting CATS prisms indicated a significant sustained relative increase in the differential IOP between the two prisms after CXL (p =.002,0.051,0.062). CH initially decreased at two weeks post-CXL then returned to sustained pre-op levels (p =.033,0.20,0.20). CCT progressively decreased following CXL (p =.005). Discussion: Differential tonometry between standard GAT and corneal biomechanical compensating CATS prisms indicates findings consistent with increased corneal rigidity following CXL and may demonstrate a simple and sensitive method for measurement of relative corneal biomechanical changes due to pharmacologic agents and procedures. [ABSTRACT FROM AUTHOR] |
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