Bibliographic Details
Title: |
Outcomes of infants with severe bronchopulmonary dysplasia in the pediatric intensive care unit. |
Authors: |
Choi, Yu Hyeon1, An, Hong Yul1, Kim, You Sun1, Park, June Dong1 jdparkmd@snu.ac.kr |
Source: |
Pediatrics International. May2021, Vol. 63 Issue 5, p529-535. 7p. |
Subject Terms: |
*INTENSIVE care units, *EVALUATION of medical care, *LENGTH of stay in hospitals, *TRACHEOTOMY, *PULMONARY hypertension, *PEDIATRICS, *TERTIARY care, *RETROSPECTIVE studies, *SEVERITY of illness index, *BRONCHOPULMONARY dysplasia, *COMORBIDITY |
Abstract: |
Background: Some infants with severe bronchopulmonary dysplasia (sBPD) are referred to higher‐level centers for multidisciplinary care, including the pediatric intensive care unit (PICU). However, information regarding these infants is limited in PICUs. Methods: We investigated the characteristics and outcomes of preterm infants with sBPD referred to the PICU of a tertiary hospital. This retrospective cohort study included 14 preterm infants with sBPD who were transferred to the PICU beyond 40 weeks' postmenstrual age (PMA) because of weaning failure, from January 1, 2014, to September 30, 2018. Results: The median age at referral was 47.1 weeks (range, 43.6–55.9 weeks), and the median length of stay in the previous neonatal intensive care unit was 154 days (range, 105.8–202.3 days) after birth. After referral the following major comorbidities were found in the patients: large airway malacia, n = 7 (50.0%); significant upper airway obstruction, n = 3 (21.4%); and pulmonary arterial hypertension, n = 8 patients (57.1%). Finally, eight patients (57.1%) were successfully extubated without tracheostomy. Final respiratory support of the patients was determined at a median PMA of 56 weeks (range, 48–63 weeks). Age at referral (P = 0.023) and large airway obstruction (P = 0.028) were significantly related to a decrease in successful extubation. Conclusion: Based on a timely and individualized multidisciplinary approach, some of the prolonged ventilator‐dependent infants, even those beyond term age, could be successfully extubated. [ABSTRACT FROM AUTHOR] |
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Database: |
Academic Search Complete |