Bibliographic Details
| Title: |
Kidney replacement therapy in pediatric patients on mechanical circulatory support: challenges for the pediatric nephrologist. |
| Authors: |
Idrovo, Alexandra1 acidrovo@texaschildrens.org, Afonso, Natasha2, Price, Jack2,3, Tume, Sebastian2, Akcan-Arikan, Ayse1,2 |
| Source: |
Pediatric Nephrology. May2021, Vol. 36 Issue 5, p1109-1117. 9p. 4 Diagrams, 2 Charts. |
| Subject Terms: |
*THERAPEUTICS, *ARTIFICIAL blood circulation, *RENAL replacement therapy, *PEDIATRICS |
| Abstract: |
The use of mechanical circulatory support (MCS) therapies in children with medically refractory cardiac failure has increased over the past two decades. With the growing experience and expertise, MCS is currently offered as a bridge to recovery or heart transplantation and in some cases even as destination therapy. Acute kidney injury (AKI) is common in patients with end-stage heart failure (ESHF). When severe AKI develops requiring kidney replacement therapy (KRT), these patients present unique challenges for the pediatric nephrology team. The use of KRT has not been adequately described in children with ESHF on the newer MCS. We also present original case series data from our center experience. The purpose of this review is to familiarize the reader with the current MCS technologies, approach to their selection, how they interact when combined with current KRT circuits, and distinguish similarities and differences. We will attempt to highlight the distinctive features of each technology, specifically focusing on growing trends in use of continuous-flow ventricular assist devices (CF-VAD) as it poses additional challenges to the pediatric nephrologist. [ABSTRACT FROM AUTHOR] |
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Copyright of Pediatric Nephrology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
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