Bibliographic Details
| Title: |
Structures and an activation mechanism of human potassium-chloride cotransporters. |
| Authors: |
Yuan Xie1, Shenghai Chang1,2, Cheng Zhao1, Feng Wang3, Si Liu4, Jin Wang5, Delpire, Eric6 eric.delpire@vanderbilt.edu, Sheng Ye4,7 sye@tju.edu.cn, Jiangtao Guo1,8 jiangtaoguo@zju.edu.cn |
| Source: |
Science Advances. 12/9/2020, Vol. 6 Issue 50, p1-10. 10p. |
| Subject Terms: |
*LABORATORY management, *GLYCINE, *GLYCINE receptors, *TYROSINE, *FLUORESCENCE resonance energy transfer |
| Abstract: |
The article presents a study which examined the structures and activation mechanism of human potassium-chloride cotransporters KCC1 to KCC4. Other topics include the role of human cation-chloride cotransporters (CCC) in homeostasis, the presence of CCCs in the tissues of brain, kidney, lung and other body parts, and the interaction of C-terminal domain (CTD) with N-terminal inhibitory peptide. |
| Database: |
Academic Search Complete |
