Amiodarone-Associated Myxedema Coma.

Bibliographic Details
Title: Amiodarone-Associated Myxedema Coma.
Authors: Zagorski, Emily1 Emily.zagorski@towerhealth.org, Jayatilaka, Sahani1, Hirani, Fizza1, Donato, Anthony1
Source: American Journal of Case Reports. 10/10/2020, Vol. 21, p1-3. 3p.
Subject Terms: *HYPONATREMIA, *THYROID gland function tests, *COMA, *CONGENITAL hypothyroidism, *ATRIAL fibrillation, *THYROID gland, *OLDER people
Abstract: Objective: Rare disease Background: Myxedema coma is an uncommon severe thyroid disorder that is fatal in 25-60% of cases. Although the differential diagnosis for altered mental status is extensive, including many more common causes such as infection, medication changes, electrolyte abnormalities, and exacerbation of chronic illnesses, profound hypothyroidism is an uncommon cause that can be overlooked. Case Report: We describe the case of a 71-year-old man on long-term amiodarone treatment for atrial fibrillation who presented with altered mental status initially ascribed to uremia, hyponatremia, and pneumonia. When his mental status did not resolve, thyroid tests showed his thyroid-stimulating hormone level was 89 µIU/mL, along with clinical criteria for myxedema coma. Conclusions: We suggest that thyroid function tests should be considered in encephalopathic older adults on amiodarone. [ABSTRACT FROM AUTHOR]
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Database: Academic Search Complete
More Details
ISSN:19415923
DOI:10.12659/AJCR.926757
Published in:American Journal of Case Reports
Language:English