Bibliographic Details
| Title: |
Glanzmann's Thrombasthenia, Correlation by Flow, Platelet Aggregometry and Platelet Function Assay (PFA). |
| Authors: |
Majed, Kameela Sayed1 kfadhel@health.gov.bh, Al-Nounou, Randa2 |
| Source: |
Bahrain Medical Bulletin. Mar2015, Vol. 37 Issue 1, p46-49. 4p. |
| Subject Terms: |
*BLOOD platelet disorders, *PLATELET function tests, *SEX distribution, *IMMUNOPHENOTYPING, *FLOW cytometry, *GENETICS, *DIAGNOSIS |
| Abstract: |
Objective: To evaluate Glanzmann's Thrombasthenia (GT) as an inherited bleeding disorder, its age and gender distribution. Design: A Retrospective Study. Setting: King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. Method: Patients were tested for Glanzmann's Thrombasthenia by platelet immunophenotyping from January 2005 to December 2009. The results of platelet immunophenotyping were compared with PFA and platelet aggregometry. Result: Thirty-three (77.3%) were type I, 7 (13.6%) were type II and 4 (9.1%) were type III. GT was mainly found in females and in pediatric age group. There was a good correlation between flow cytometry study and aggregation study. Conclusion: GT is a common bleeding disorder in a community where consanguineous marriage is common. [ABSTRACT FROM AUTHOR] |
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| Database: |
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