Multifaceted Roles of Crystallography in Modern Drug Discovery

Table of Contents: “…-Protein-Ligand Interactions as the Basis for Drug Action -- The Protein Data Bank: Overview and Tools for Drug Discovery -- Small Molecule Crystal Structures in Drug Discovery -- Protein Aggregation and its Prediction -- Importance of Protonation States for the Binding of Ligands to Pharmaceutical Targets -- Protein-Protein Interactions: Structures and Druggability -- Achieving High Quality Ligand Chemistry in Protein-Ligand Crystal Structures for Drug Design -- Molecular Obesity, Potency and Other Addictions in Drug Discovery -- Adventures in Small Molecule Fragment Screening by X-ray Crystallography for Drug Discovery -- Structure-Based Drug Design to Perturb Function of a tRNA-Modifying Enzyme by Active Site and Protein-Protein Interface Inhibition -- Molecular Interaction Analysis for Discovery of Drugs Targeting Enzymes and for Resolving Biological Function.…”
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Principles of computational cell biology : from protein complexes to cellular networks by Helms, Volkhard

Table of Contents: Connect to this title online (unlimited simultaneous users allowed; 325 uses per year)

F# for scientists by Harrop, Jon D.

Table of Contents: “…Loading .NET libraries -- Charting and graphing -- Threads -- Random numbers -- Regular expressions -- Vectors and matrices -- Downloading from the Web -- Compression -- Handling XML -- Calling native libraries -- Fourier transform -- Metaprogramming -- Databases. Protein data bank -- Web services -- Relational databases -- Interoperability. …”
Available online from O'Reilly Online Learning Platform: Academic Edition (EZproxy Access): 2008

Concepts and techniques in omics and system biology by Zargar, Sajad Majeed

Table of Contents: “…3 -- Advances in proteomics techniques -- Introduction -- MASCOT -- pQuant software -- Trans Proteomic Pipeline (TPP) software -- Census software -- MaxQuant software -- Advanced features -- Exploring proteome databases -- UniProt -- NCBI protein -- Ensembl -- Protein Data Bank -- PeptideAtlas -- Human protein Atlas -- PRIDE database -- Human proteome organization proteomics standards initiative repositories -- RefSeq -- SWISS-MODEL repository -- Conclusion -- References -- Further reading -- 4 -- Aspects of protein interactions -- Coimmuno precipitation -- Antibody selection -- Cell lysis…”
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Leadership in science and technology : a reference handbook

Table of Contents: “…Vertesi -- The Perseus Project / Gregory Crane -- Polar Research / Fae L. Korsmo -- The Protein Data Bank / Helen M. Berman -- Social Science Data Archives / Roger Finke, Christopher D. …”
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