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Cycling above rather than below lactate threshold is more effective for nitric oxide release and post-exercise blood pressure reduction in individuals with type-2 diabetes

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Title: Cycling above rather than below lactate threshold is more effective for nitric oxide release and post-exercise blood pressure reduction in individuals with type-2 diabetes
Authors: Asano, Ricardo Yukio, Browne, Rodrigo Alberto Vieira, Sotero, Rafael da Costa, Sales, Marcelo Magalhães, Moraes, José Fernando Vila Nova de, Campbell, Carmen Sílvia Grubert, Simões, Herbert Gustavo
Source: Motriz: Revista de Educação Física. September 2013 19(3)
Publisher Information: Universidade Estadual Paulista, 2013.
Publication Year: 2013
Subject Terms: nitric oxide, type-2 diabetes, high intensity exercise
More Details: The purposes of this study were to analyze and compare the effects of exercise performed in different intensities, above and below lactate threshold (LT) on post-exercise blood pressure (BP) and nitric oxide (NO) responses in individuals with type 2 diabetes (T2D). For this, 11 T2D underwent the following sessions: 1) control session; 2) 20-min of moderate cycling (80% LT); and 3) 20-min of high intensity cycling (120%LT) on a cycle ergometer. Plasma NO and BP measurements were carried out at rest and at 15 and 45 min of post-sessions. When compared to rest, only the exercise session performed at 120%LT elicited an increase of NO (from 7.2 to 9.5 µM, p<0.05), as well as a decrease in systolic BP (from 126.6±7.9 to 118.7±3.9 mmHg, p<0.05) during the post-exercise period. In conclusion, the results suggest that NO release and post-exercise BP decrease are intensity-dependent for individuals with T2D.
Document Type: article
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Language: English
ISSN: 1980-6574
DOI: 10.1590/S1980-65742013000300015
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  Data: The purposes of this study were to analyze and compare the effects of exercise performed in different intensities, above and below lactate threshold (LT) on post-exercise blood pressure (BP) and nitric oxide (NO) responses in individuals with type 2 diabetes (T2D). For this, 11 T2D underwent the following sessions: 1) control session; 2) 20-min of moderate cycling (80% LT); and 3) 20-min of high intensity cycling (120%LT) on a cycle ergometer. Plasma NO and BP measurements were carried out at rest and at 15 and 45 min of post-sessions. When compared to rest, only the exercise session performed at 120%LT elicited an increase of NO (from 7.2 to 9.5 &#181;M, p&lt;0.05), as well as a decrease in systolic BP (from 126.6&#177;7.9 to 118.7&#177;3.9 mmHg, p&lt;0.05) during the post-exercise period. In conclusion, the results suggest that NO release and post-exercise BP decrease are intensity-dependent for individuals with T2D.
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