Academic Journal
Placental genomics mediates genetic associations with complex health traits and disease
Title: | Placental genomics mediates genetic associations with complex health traits and disease |
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Authors: | Arjun Bhattacharya, Anastasia N. Freedman, Vennela Avula, Rebeca Harris, Weifang Liu, Calvin Pan, Aldons J. Lusis, Robert M. Joseph, Lisa Smeester, Hadley J. Hartwell, Karl C. K. Kuban, Carmen J. Marsit, Yun Li, T. Michael O’Shea, Rebecca C. Fry, Hudson P. Santos |
Source: | Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022) |
Publisher Information: | Nature Portfolio, 2022. |
Publication Year: | 2022 |
Collection: | LCC:Science |
Subject Terms: | Science |
More Details: | The impact of placental transcriptomics on fetal traits throughout development is not well understood. Here, the authors apply distal-SNP-enriched transcriptome-wide association studies to detect genetic contributions, mediated through fetal placental genomics, to developmental programming of complex traits across the life course. |
Document Type: | article |
File Description: | electronic resource |
Language: | English |
ISSN: | 2041-1723 |
Relation: | https://doaj.org/toc/2041-1723 |
DOI: | 10.1038/s41467-022-28365-x |
Access URL: | https://doaj.org/article/f834790b97534f809de5e0b70af87c2e |
Accession Number: | edsdoj.f834790b97534f809de5e0b70af87c2e |
Database: | Directory of Open Access Journals |
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