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Clinical outcomes of patients undergoing percutaneous left atrial appendage occlusion in general anaesthesia or conscious sedation: data from the prospective global Amplatzer Amulet Occluder Observational Study

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Title: Clinical outcomes of patients undergoing percutaneous left atrial appendage occlusion in general anaesthesia or conscious sedation: data from the prospective global Amplatzer Amulet Occluder Observational Study
Authors: Matteo Montorfano, Kerstin Piayda, Katharina Hellhammer, Sergio Berti, Jens Erik Nielsen-Kudsk, Boris Schmidt, Patrizio Mazzone, Sven Fischer, Juha Lund, Paolo Della Bella, Ryan Gage, Tobias Zeus
Source: BMJ Open, Vol 11, Iss 3 (2021)
Publisher Information: BMJ Publishing Group, 2021.
Publication Year: 2021
Collection: LCC:Medicine
Subject Terms: Medicine
More Details: Objective To evaluate the safety and efficacy of percutaneous left atrial appendage occlusion (LAAO) using conscious sedation (CS).Background Several percutaneous structural heart disease interventions are safely and efficiently performed using CS instead of general anaesthesia (GA). This concept has not been evaluated in a large multicenter cohort of patients undergoing LAAO.Methods Patients from the prospective, global Amplatzer Amulet Occluder Observational Study were divided into two groups (GA vs CS). Baseline information, periprocedural and postprocedural efficacy and complications, as well as outcomes through 7 days post implant were compared.Results Patients undergoing transesophageal-guided implants were categorised by GA (n=607, 64%) or CS (n=342, 36%) usage. Mean age was 75 years in both groups. LAAO technical success was achieved in 99% of both groups. The procedure duration (GA: 35±22 min vs CS: 27±19 min, p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2020-0404
2044-6055
Relation: https://bmjopen.bmj.com/content/11/3/e040455.full; https://doaj.org/toc/2044-6055
DOI: 10.1136/bmjopen-2020-040455
Access URL: https://doaj.org/article/bf4b85d2ec28401cbc495d46294c601a
Accession Number: edsdoj.bf4b85d2ec28401cbc495d46294c601a
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  Data: Clinical outcomes of patients undergoing percutaneous left atrial appendage occlusion in general anaesthesia or conscious sedation: data from the prospective global Amplatzer Amulet Occluder Observational Study
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  Data: <searchLink fieldCode="AR" term="%22Matteo+Montorfano%22">Matteo Montorfano</searchLink><br /><searchLink fieldCode="AR" term="%22Kerstin+Piayda%22">Kerstin Piayda</searchLink><br /><searchLink fieldCode="AR" term="%22Katharina+Hellhammer%22">Katharina Hellhammer</searchLink><br /><searchLink fieldCode="AR" term="%22Sergio+Berti%22">Sergio Berti</searchLink><br /><searchLink fieldCode="AR" term="%22Jens+Erik+Nielsen-Kudsk%22">Jens Erik Nielsen-Kudsk</searchLink><br /><searchLink fieldCode="AR" term="%22Boris+Schmidt%22">Boris Schmidt</searchLink><br /><searchLink fieldCode="AR" term="%22Patrizio+Mazzone%22">Patrizio Mazzone</searchLink><br /><searchLink fieldCode="AR" term="%22Sven+Fischer%22">Sven Fischer</searchLink><br /><searchLink fieldCode="AR" term="%22Juha+Lund%22">Juha Lund</searchLink><br /><searchLink fieldCode="AR" term="%22Paolo+Della+Bella%22">Paolo Della Bella</searchLink><br /><searchLink fieldCode="AR" term="%22Ryan+Gage%22">Ryan Gage</searchLink><br /><searchLink fieldCode="AR" term="%22Tobias+Zeus%22">Tobias Zeus</searchLink>
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  Data: BMJ Open, Vol 11, Iss 3 (2021)
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  Data: Objective To evaluate the safety and efficacy of percutaneous left atrial appendage occlusion (LAAO) using conscious sedation (CS).Background Several percutaneous structural heart disease interventions are safely and efficiently performed using CS instead of general anaesthesia (GA). This concept has not been evaluated in a large multicenter cohort of patients undergoing LAAO.Methods Patients from the prospective, global Amplatzer Amulet Occluder Observational Study were divided into two groups (GA vs CS). Baseline information, periprocedural and postprocedural efficacy and complications, as well as outcomes through 7 days post implant were compared.Results Patients undergoing transesophageal-guided implants were categorised by GA (n=607, 64%) or CS (n=342, 36%) usage. Mean age was 75 years in both groups. LAAO technical success was achieved in 99% of both groups. The procedure duration (GA: 35±22 min vs CS: 27±19 min, p
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