The prevalence of human polyomaviruses in urine samples of immunocompetent individuals in the Serbian population
| Title: | The prevalence of human polyomaviruses in urine samples of immunocompetent individuals in the Serbian population |
|---|---|
| Authors: | Karalić Danijela, Lazarević Ivana, Ćupić Maja, Jovanović Tanja |
| Source: | Archives of Biological Sciences, Vol 64, Iss 4, Pp 1383-1388 (2012) |
| Publisher Information: | University of Belgrade, University of Novi Sad, 2012. |
| Publication Year: | 2012 |
| Collection: | LCC:Biology (General) |
| Subject Terms: | human polyomaviruses, immunocompetent, urinary excretion, Biology (General), QH301-705.5 |
| More Details: | The BK (BKV) and JC viruses (JCV) are human polyomaviruses. After primary infection, they persist as latent infection in the kidneys. Immunosuppression leads to their reactivation, which is associated with life-threatening diseases such as polyomavirus-induced nephropathy and progressive multifocal leukoencephalopathy. However, the behavior of these viruses in immunocompetent individuals is still an open question with no right answer. The aim of this study was to determine the prevalence of BKV and JCV shedding in the urine of immunocompetent individuals from the Serbian population. Sixty-five urine samples were collected and tested for the presence of BKV and JCV DNA by PCR. JCV DNA was detected in 19/65 (29.2%) and BKV DNA in 3/65 (4.6%) of the urine samples. Forty-three (66.2%) urine samples of the immunocompetent donors were negative for both viruses. The present study provides the first results of urinary excretion of human polyomaviruses in the Serbian population. [Projekat Ministarstva nauke Republike Srbije, br. 175073] |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0354-4664 1821-4339 |
| Relation: | https://doaj.org/toc/0354-4664; https://doaj.org/toc/1821-4339 |
| DOI: | 10.2298/ABS1204383K |
| Access URL: | https://doaj.org/article/b7584ba5334d41e483fac827dad27268 |
| Accession Number: | edsdoj.b7584ba5334d41e483fac827dad27268 |
| Database: | Directory of Open Access Journals |
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