Effect of epidural block on surgical conditions during pediatric subumbilical laparoscopic surgery involving a supraglottic airway: a randomized clinical trial

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Title: Effect of epidural block on surgical conditions during pediatric subumbilical laparoscopic surgery involving a supraglottic airway: a randomized clinical trial
Authors: Lei Wu, Siwei Wei, Zhen Xiang, Eryou Yu, Zheng Chen, Zhen Du, Shuang Quan Qu
Source: Frontiers in Medicine, Vol 10 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Medicine (General)
Subject Terms: supraglottic airway, laryngeal mask airway, neuromuscular block, epidural block, pediatric laparoscopy, surgical conditions, Medicine (General), R5-920
More Details: BackgroundFew studies have examined the effect of epidural block on surgical conditions during pediatric subumbilical laparoscopic surgery involving a supraglottic airway (SGA). This study investigated the surgical condition scores for such procedures in cases where neuromuscular block, epidural block, or neither was used.MethodsA total of 150 patients aged 3–12 years undergoing laparoscopic orchiopexy with a ProSeal SGA device were randomly allocated to one of three groups: the control group (did not receive neuromuscular block and epidural block), the NMB group [received a neuromuscular block (train-of-four 1–2 twitches) using rocuronium], or the EDB group (received an epidural block using ropivacaine). The primary outcome was the quality of surgical conditions evaluated with the Leiden-Surgical Rating Scale by the blinded surgeon. The secondary outcome measures included intraoperative hemodynamic data (including mean arterial pressure and heart rate), the SGA device removal time, the PACU discharge time, the pain score in the PACU and intraoperative adverse events (including bradycardia, hypotension, peak airway pressure > 20 cmH2O, and poor or extremely poor surgical conditions occurred during the operation). Statistical analysis was performed with one-way analysis of variance, the Kruskal–Wallis test, the chi-square test or Fisher’s exact test. Bonferroni corrections for multiple comparisons were made for primary and secondary outcomes.ResultsSurgical condition scores were significantly higher in the NMB and EDB groups than in the control group (median difference: 0.8; 95% confidence interval [CI], 0.5–1.0; p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2296-858X
Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1250039/full; https://doaj.org/toc/2296-858X
DOI: 10.3389/fmed.2023.1250039
Access URL: https://doaj.org/article/9355406113304689a687c94d2d3d854b
Accession Number: edsdoj.9355406113304689a687c94d2d3d854b
Database: Directory of Open Access Journals
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  Data: Effect of epidural block on surgical conditions during pediatric subumbilical laparoscopic surgery involving a supraglottic airway: a randomized clinical trial
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  Data: <searchLink fieldCode="AR" term="%22Lei+Wu%22">Lei Wu</searchLink><br /><searchLink fieldCode="AR" term="%22Siwei+Wei%22">Siwei Wei</searchLink><br /><searchLink fieldCode="AR" term="%22Zhen+Xiang%22">Zhen Xiang</searchLink><br /><searchLink fieldCode="AR" term="%22Eryou+Yu%22">Eryou Yu</searchLink><br /><searchLink fieldCode="AR" term="%22Zheng+Chen%22">Zheng Chen</searchLink><br /><searchLink fieldCode="AR" term="%22Zhen+Du%22">Zhen Du</searchLink><br /><searchLink fieldCode="AR" term="%22Shuang+Quan+Qu%22">Shuang Quan Qu</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22supraglottic+airway%22">supraglottic airway</searchLink><br /><searchLink fieldCode="DE" term="%22laryngeal+mask+airway%22">laryngeal mask airway</searchLink><br /><searchLink fieldCode="DE" term="%22neuromuscular+block%22">neuromuscular block</searchLink><br /><searchLink fieldCode="DE" term="%22epidural+block%22">epidural block</searchLink><br /><searchLink fieldCode="DE" term="%22pediatric+laparoscopy%22">pediatric laparoscopy</searchLink><br /><searchLink fieldCode="DE" term="%22surgical+conditions%22">surgical conditions</searchLink><br /><searchLink fieldCode="DE" term="%22Medicine+%28General%29%22">Medicine (General)</searchLink><br /><searchLink fieldCode="DE" term="%22R5-920%22">R5-920</searchLink>
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  Data: BackgroundFew studies have examined the effect of epidural block on surgical conditions during pediatric subumbilical laparoscopic surgery involving a supraglottic airway (SGA). This study investigated the surgical condition scores for such procedures in cases where neuromuscular block, epidural block, or neither was used.MethodsA total of 150 patients aged 3–12 years undergoing laparoscopic orchiopexy with a ProSeal SGA device were randomly allocated to one of three groups: the control group (did not receive neuromuscular block and epidural block), the NMB group [received a neuromuscular block (train-of-four 1–2 twitches) using rocuronium], or the EDB group (received an epidural block using ropivacaine). The primary outcome was the quality of surgical conditions evaluated with the Leiden-Surgical Rating Scale by the blinded surgeon. The secondary outcome measures included intraoperative hemodynamic data (including mean arterial pressure and heart rate), the SGA device removal time, the PACU discharge time, the pain score in the PACU and intraoperative adverse events (including bradycardia, hypotension, peak airway pressure > 20 cmH2O, and poor or extremely poor surgical conditions occurred during the operation). Statistical analysis was performed with one-way analysis of variance, the Kruskal–Wallis test, the chi-square test or Fisher’s exact test. Bonferroni corrections for multiple comparisons were made for primary and secondary outcomes.ResultsSurgical condition scores were significantly higher in the NMB and EDB groups than in the control group (median difference: 0.8; 95% confidence interval [CI], 0.5–1.0; p
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        Value: 10.3389/fmed.2023.1250039
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      – Text: English
    Subjects:
      – SubjectFull: supraglottic airway
        Type: general
      – SubjectFull: laryngeal mask airway
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      – SubjectFull: neuromuscular block
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      – SubjectFull: surgical conditions
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      – TitleFull: Effect of epidural block on surgical conditions during pediatric subumbilical laparoscopic surgery involving a supraglottic airway: a randomized clinical trial
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