Translation, Cross-Cultural Adaptation, Reliability and Construct Validity of the FACT- EGFRI-18 Quality of Life Instrument from English into Portuguese

Bibliographic Details
Title: Translation, Cross-Cultural Adaptation, Reliability and Construct Validity of the FACT- EGFRI-18 Quality of Life Instrument from English into Portuguese
Authors: Luiza Erthal de Britto Pereira Kassuga Roisman, Anke Bergmann, Luiz Claudio Santos Thuler
Source: Revista Brasileira de Cancerologia, Vol 70, Iss 3 (2024)
Publisher Information: Instituto Nacional de Câncer (INCA), 2024.
Publication Year: 2024
Collection: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms: ErbB Receptors, Translating, Reproducibility of Results, Surveys and Questionnaires, Quality of Life, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details: Introduction: Adverse epidermal growth factor receptor (EGFR) dermatological events affect many patients and can impair the patient’s quality of life (QoL), leading to dose reduction or discontinuation of therapy. Objective: To carry out the translation, cross-cultural adaptation, reliability and validity of the Functional Evaluation of Cancer Therapy - Epidermal Growth Factor Receptor Inhibitor 18 (FACT-EGFRI-18) to be utilized in Portuguese. Method: Study to evaluate the cross-cultural adaptation, reliability and construct validation of the FACT-EGFRI-18 translated into Portuguese. To evaluate cross-cultural adaptation, semantic analysis was performed by ten patients and content analysis by experts. Reliability was assessed by internal consistency analysis using Cronbach’s alpha coefficient. Construct validity was determined by the correlation between the translated FACT-EGFRI-18 and the Dermatology Life Quality Index (DLQI) answered by 30 participants with cancer undergoing treatment with EGFR. A descriptive analysis of the study population was performed and Cronbach’s alpha coefficient was calculated to determine the internal consistency of the Portuguese version of the FACTEGFRI- 18 and Pearson’s demonstration coefficient was applied to determine the transparency between the questionnaires. ANOVA test was performed to compare the mean FACT-EGFRI-18 score according to demographic variables. Results: The semantic evaluation showed that all the participants understood the items of the translated questionnaire, which revealed strong internal consistency (Cronbach’s alpha = 0.89) and validity (Pearson's correlation = 0.66). Conclusion: The FACT-EGFRI-18 was easily understood by the patients and the results support its reliability and validity.
Document Type: article
File Description: electronic resource
Language: English
Spanish; Castilian
Portuguese
ISSN: 2176-9745
Relation: https://rbc.inca.gov.br/index.php/revista/article/view/4672; https://doaj.org/toc/2176-9745
DOI: 10.32635/2176-9745.RBC.2024v70n3.4672
Access URL: https://doaj.org/article/92f2a5700a544ee497d6af59a5bfa253
Accession Number: edsdoj.92f2a5700a544ee497d6af59a5bfa253
Database: Directory of Open Access Journals
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  Data: Translation, Cross-Cultural Adaptation, Reliability and Construct Validity of the FACT- EGFRI-18 Quality of Life Instrument from English into Portuguese
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  Data: Revista Brasileira de Cancerologia, Vol 70, Iss 3 (2024)
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  Data: Instituto Nacional de Câncer (INCA), 2024.
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  Data: 2024
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  Data: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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– Name: Abstract
  Label: Description
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  Data: Introduction: Adverse epidermal growth factor receptor (EGFR) dermatological events affect many patients and can impair the patient’s quality of life (QoL), leading to dose reduction or discontinuation of therapy. Objective: To carry out the translation, cross-cultural adaptation, reliability and validity of the Functional Evaluation of Cancer Therapy - Epidermal Growth Factor Receptor Inhibitor 18 (FACT-EGFRI-18) to be utilized in Portuguese. Method: Study to evaluate the cross-cultural adaptation, reliability and construct validation of the FACT-EGFRI-18 translated into Portuguese. To evaluate cross-cultural adaptation, semantic analysis was performed by ten patients and content analysis by experts. Reliability was assessed by internal consistency analysis using Cronbach’s alpha coefficient. Construct validity was determined by the correlation between the translated FACT-EGFRI-18 and the Dermatology Life Quality Index (DLQI) answered by 30 participants with cancer undergoing treatment with EGFR. A descriptive analysis of the study population was performed and Cronbach’s alpha coefficient was calculated to determine the internal consistency of the Portuguese version of the FACTEGFRI- 18 and Pearson’s demonstration coefficient was applied to determine the transparency between the questionnaires. ANOVA test was performed to compare the mean FACT-EGFRI-18 score according to demographic variables. Results: The semantic evaluation showed that all the participants understood the items of the translated questionnaire, which revealed strong internal consistency (Cronbach’s alpha = 0.89) and validity (Pearson's correlation = 0.66). Conclusion: The FACT-EGFRI-18 was easily understood by the patients and the results support its reliability and validity.
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        Value: 10.32635/2176-9745.RBC.2024v70n3.4672
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      – Text: English
      – Text: Spanish; Castilian
      – Text: Portuguese
    Subjects:
      – SubjectFull: ErbB Receptors
        Type: general
      – SubjectFull: Translating
        Type: general
      – SubjectFull: Reproducibility of Results
        Type: general
      – SubjectFull: Surveys and Questionnaires
        Type: general
      – SubjectFull: Quality of Life
        Type: general
      – SubjectFull: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
        Type: general
      – SubjectFull: RC254-282
        Type: general
    Titles:
      – TitleFull: Translation, Cross-Cultural Adaptation, Reliability and Construct Validity of the FACT- EGFRI-18 Quality of Life Instrument from English into Portuguese
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            NameFull: Luiza Erthal de Britto Pereira Kassuga Roisman
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            NameFull: Anke Bergmann
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            NameFull: Luiz Claudio Santos Thuler
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              Y: 2024
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